Abstract
The purpose of this study was to determine the usefulness of magnetic resonance imaging
(MRI) for distinguishing spinal involvement of hematopoietic malignancies (lymphoma,
leukemia, and multiple myeloma) from metastasis. 62 spinal MRIs were obtained in 60
patients with hematopoietic malignancies (n = 24) and metastasis (n = 36) in clinically
and pathologically proven cases. MRI findings were evaluated in each group of patients
for the pattern of involvement, signal change of vertebral body, location of paraspinal
mass formation, location of epidural mass formation, cortical destruction, contour
change, and compression fracture. Diffuse involvements were more commonly seen in
hematopoietic malignancies than in metastasis (p < 0.05). Signal change confined to
anterior element was seen in 9 metastasis but was not seen in hematopoietic malignancies.
Cortical destructions were more commonly seen in metastasis than in hematopoietic
malignancies (p < 0.05). Other findings did not show any statistical significance
in both groups. MRI findings such as diffuse involvement, posterior epidural mass
formation, and cortical destruction were useful to distinguish spinal involvement
of hematopoietic malignancies and metastasis.
Keywords
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Article info
Publication history
Accepted:
December 15,
1998
Received:
November 11,
1998
Identification
Copyright
© 1999 Elsevier Science Inc. Published by Elsevier Inc. All rights reserved.
