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Neurosarcoidosis presenting as a large suprasellar mass

Magnetic resonance imaging findings
  • Rohit Bakshi
    Correspondence
    Address correspondence to: Rohit Bakshi, MD, Lucy Dent Imaging Center, 3 Gates Circle, Buffalo, New York 14209
    Affiliations
    From the Millard Fillmore Health System, Lucy Dent Imaging Center, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York USA.

    Dent Neurologic Institute, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York USA.

    Departments of Neurology, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York USA.
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  • Robert A Fenstermaker
    Affiliations
    Neurosurgery, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York USA.
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  • Vernice E Bates
    Affiliations
    From the Millard Fillmore Health System, Lucy Dent Imaging Center, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York USA.

    Dent Neurologic Institute, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York USA.

    Departments of Neurology, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York USA.
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  • T.P Ravichandran
    Affiliations
    From the Millard Fillmore Health System, Lucy Dent Imaging Center, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York USA.
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  • Sam Goodloe Jr.
    Affiliations
    Pathology, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York USA.
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  • William R Kinkel
    Affiliations
    From the Millard Fillmore Health System, Lucy Dent Imaging Center, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York USA.

    Dent Neurologic Institute, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York USA.

    Departments of Neurology, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York USA.
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      Abstract

      We present unusual magnetic resonance imaging (MRI) findings in a case of neurosarcoidosis. MRI revealed a large solitary suprasellar mass which resembled a neoplasm. The lesion was isointense and hyperintense on T1-weighted images, hypointense on T2-weighted images, and intensely homogeneously enhancing. Biopsy revealed a polymorphous inflammatory lesion with giant cells, which extended from the hypothalamus, consistent with neurosarcoidosis. The diagnosis of neurosarcoidosis should be considered in patients presenting with large midline tumor-like suprasellar mass lesions.

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      References

        • Case records of the Massachusetts General Hospital
        Case 37-1996.
        N Engl J Med. 1996; 335: 1668-1674
        • Grand S.
        • Hoffmann D.
        • Bost F.
        • Francois-Joubert A.
        • Pasquier B.
        • Le Bas J.F.
        Case report.
        Br J Radiol. 1996; 69: 272-275
        • Hayes W.S.
        • Sherman J.L.
        • Stern B.J.
        • Citrin C.M.
        • Pulaski P.D.
        MR and CT evaluation of intracranial sarcoidosis.
        AJNR. 1987; 8: 841-847
        • Lexa F.J.
        • Grossman R.I.
        MR of sarcoidosis in the head and spine.
        AJNR. 1994; 15: 973-982
        • Liu D.P.C.
        • Sze G.
        Intracranial sarcoidosis on gadolinium-enhanced MRI.
        Neuroradiology. 1991; 33: 189
        • Miller D.H.
        • Kendall B.E.
        • Barter S.
        • et al.
        Magnetic resonance imaging in central nervous system sarcoidosis.
        Neurology. 1988; 38: 378-383
        • Mirfakhraee M.
        • Crofford M.J.
        • Guinto F.C.
        • Nauta H.J.W.
        • Weedn V.W.
        Virchow-Robin space.
        Radiology. 1986; 158: 715-720
        • Seltzer S.
        • Mark A.S.
        • Atlas S.W.
        CNS sarcoidosis.
        AJNR. 1991; 12: 1227-1233
        • Sherman J.L.
        • Stern B.J.
        Sarcoidosis of the CNS.
        AJNR. 1990; 11: 915-923
        • Stubgen J.-P.
        Neurosarcoidosis presenting as a retroclival mass.
        Surg Neurol. 1995; 43: 85-88
        • Ulmer J.L.
        • Elster A.D.
        Sarcoidosis of the central nervous system.
        Neuroimag Clin N Am. 1991; 1: 141-158
        • Wilson J.D.
        • Castillo M.
        Magnetic resonance imaging of granulomatous inflammations.
        Top Magn Res Imag. 1994; 6: 32-40
        • Wilson J.D.
        • Castillo M.
        • Van Tassel P.
        MRI features of intracranial sarcoidosis mimicking meningiomas.
        Clin Imag. 1994; 18: 184-188
        • Scott T.F.
        Neurosarcoidosis.
        Neurology. 1993; 43: 8-12