Abstract
We performed a prospective study from November 1989 to December 1996 to assess the
accuracy of endoscopic ultrasonography (EUS) in the locoregional staging and resectability
of patients with gastric carcinoma. One hundred and nineteen patients with gastric
cancer who received preoperative assessment by EUS underwent subsequent surgery. The
endosonographic tumor-node-metastasis (TNM) classification was used for comparison
with the histopathologic findings of the resected specimens. The ability of EUS to
accurately predict the T stage (depth of tumor invasion) and N stage (involvement
of lymph node) was 70% and 65%, respectively. EUS dis- played a tendency to overestimate
T stage and underestimate N stage. The differentiation of early gastric cancer from
advanced gastric cancer showed a concordance rate of 89% with an overestimation rate
of 8% and underestimation rate of 3%. The accuracy of EUS in predicting the stage
T1 to T3, which correspond to D0 resectability (no macroscopic or microscopic tumor
remains), was 91%. In conclusion, these results revealed EUS as a valuable tool for
evaluating the local staging and resectability of gastric cancer. We suggest that
EUS should be introduced in the preoperative assessment of patients with gastric cancer.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Clinical ImagingAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Epidemiology of cancer of the stomach with special reference to its recent decrease in Japan.Cancer Res. 1975; 35: 3460-3463
- Decreased incidence of intestinal and diffuse types of gastric carcinoma in Finland during 20 year period.Scand J Gastroenterol. 1987; 22: 865-871
- Cancer statistics 1980.Cancer J Clinicians. 1980; 30: 23-38
- Cancer of the stomach.Br J Surg. 1976; 63: 603-607
- A co-operative international study of gastric cancer.Ann R Coll Surg Engl. 1974; 54: 219-228
- Computed tomographic staging of gastrointestinal tract malignancies.Invest Radiol. 1987; 103: 344-350
- Computed tomography in the preoperative evaluation of gastric carcinoma.Gastrointest Radiol. 1988; 13: 97-101
- MR imaging of diffusely infiltrating gastric carcinoma.J Comput Assist Tomogr. 1987; 11: 337-339
- Endoscopic ultrasonography of normal and pathologic upper gastrointestinal wall structure.Scand J Gastroenterol. 1986; 21: 27-33
- Endoscopic ultrasonography in the diagnosis of regional lymph nodes in esophageal and gastric cancer—results of studies in vitro.Endoscopy. 1993; 25: 231-235
- Manual for Staging of Cancer. 3. Lippincott, Philadelphia, PA1988 (pp. 69–74)
- Endoscopic ultrasonography in the assessment of intra and transmural infiltration of tumors in the esophagus, stomach and papilla of vater and in the detection of extra oesophageal lesions.Endoscopy. 1984; 16: 203-210
- A fundamental study of normal layer structure of the gastrointestinal wall visualized by endoscopic ultrasonography.Scand J Gastroenterol. 1986; 21: 6-15
- Upper gastrointestinal endoscopic ultrasonography in gastroenterology.Br J Radiol. 1987; 60: 429-438
- Endosonography for preoperative locoregional staging of esophageal and gastric cancer.Endoscopy. 1993; 25: 224-230
- Role of endoscopic ultrasonography in gastric carcinoma.Endoscopy. 1993; 25: 162-166
- Endosonography in the clinical staging of esophagogastric carcinoma.Gastrointest Endosc. 1990; 36: S2-S10
Article info
Publication history
Accepted:
January 25,
1998
Received:
December 20,
1997
Identification
Copyright
© 1998 Elsevier Science Inc. Published by Elsevier Inc. All rights reserved.