Abstract
We evaluated the role of computed tomography (CT)- guided transthoracic needle biopsy
(TNB) in patients with solitary pulmonary nodule and indeterminate flexible fiberoptic
bronchoscopy (FOB). A review of 112 patients with solitary nodules under 3 cm in size
who underwent TNB was carried out. A total of 48 patients had prior FOB with negative
or indeterminate results. We reviewed the results of CT-guided TNB of these 48 patients
with respect to the cytology results, nodule size and location, and complications
of the procedure. Among the 48 patients who had FOB with indeterminate cytology, 32
were found to have malignant cytology on subsequent TNB. Among the remaining 16 patients,
eight had diagnostic thoracotomy, which showed that six of the nodules were benign
and two were malignant. The remaining eight patients who did not undergo surgery have
been followed for more than 2 years, without evidence of growth. Results were not
influenced by size or location. TNB offers a high yield for diagnosis in this patient
population.
Keywords
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Article info
Publication history
Accepted:
August 1,
1996
Received:
August 1,
1996
Identification
Copyright
© 1998 Elsevier Science Inc. Published by Elsevier Inc. All rights reserved.
