CT-guided transthoracic needle biopsy of small solitary pulmonary nodules

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      The use of CT guidance in performing transthoracic needle biopsy is well established. We evaluated its accuracy in the diagnosis of small solitary nodules and found it to be highly accurate regardless of size or location. While specific benign diagnoses were uncommon, additional confidence in a benign diagnosis can be gained by careful analysis of needle tip location using strict CT criteria.


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        • Gardner D
        • Van Sonnenberg E
        • D'Agostino HB
        • Casola G
        • Taggart S
        • May S
        CT-guided transthoracic needle biopsy.
        Cardiovasc Interven Radiol. 1991; 14: 17-23
        • Westcott JL
        Needle biopsy of the chest.
        in: Tavares J Ferrucci J 2nd ed. Imaging-Diagnosis-Intervention. Volume 1. Lippincott, Philadelphia1993: 1-13 (Chapter 45)
        • Berquist TH
        • Bailey PB
        • Cortese DA
        • Miller WE
        Transthoracic needle biopsy: accuracy and complications in relation to location and type of lesion.
        in: 2nd ed. Mayo Clin Proc. 55. 1980: 475-481
        • Wallace JM
        • Deutsch AL
        Flexible fiberoptic bronchoscopy and percutaneous needle lung aspiration for evaluating the solitary pulmonary nodule.
        Chest. 1982; 81: 665-671
        • Khouri NF
        • Stitik FP
        • Erozen YS
        • et al.
        Transthoracic needle aspiration biopsy of benign and malignant lung lesions.
        AJR. 1985; 144: 281-288
        • Westcott JL
        Direct percutaneous needle aspiration of localized pulmonary lesions: results in 422 patients.
        Radiology. 1980; 137: 31-35
        • Jereb M
        The usefulness of needle biopsy in chest lesions of different sizes and locations.
        Radiology. 1980; 134: 13-15
        • Van Sonnenberg E
        • Casola G
        • Ho M
        • Neff CC
        • Varney RR
        • Witlich GR
        • Christensen R
        • Friedman PJ
        Difficult thoracic lesions: CT-guided biopsy experience in 150 cases.
        Radiology. 1988; 167: 457-461
        • Gatenby RA
        • Mulhern CB
        • Broder GJ
        • Moldofsky PJ
        Computed-tomographic-guided biopsy of small apical and peripheral upper lobe lung masses.
        Radiology. 1984; 150: 591-592
        • Sider L
        • Davis Jr, TW
        Hilar masses: evaluation with CT-guided biopsy after negative bronchoscopic examination.
        Radiology. 1983; 164: 107-109
        • Haramati LB
        • Austin JHM
        Complications after CT-guided needle biopsy through aerated versus non-aerated lung.
        Radiology. 1991; 181: 778
        • Yankelevitz DF
        • Henschke CI
        • Davis SD
        Percutaneous CT biopsy of chest lesions: an in-vitro analysis of the effect of partial volume averaging on needle positioning.
        AJR. 1993; 161: 273-278
        • Yankelevitz DF
        • Henschke CI
        Needle tip localization for CT guided biopsies.
        J Thor Imag. 1993; 8: 241-243
        • Sargent EN
        • Turner AF
        • Gordonson J
        • et al.
        Percutaneous pulmonary needle biopsy.
        AJR. 1974; 122: 758-768
        • Calhoun P
        • Feldman PS
        • Armstrong P
        The clinical outcome of needle aspirations of the lung when cancer is not diagnosed.
        Ann Thor Surg. 1986; 41: 592-596