Abstract
The American Thoracic Society provides guidelines for the confident radiographic diagnosis
of UIP. In addition, the guidelines identify findings on CT scans that should suggest
an alternative diagnosis to UIP. These findings include consolidation, air trapping,
nodules, ground glass opacities, cysts, and upper lung and bronchovascular distribution.
We present a mnemonic to help the reader remember the list of findings that are inconsistent
with UIP and provide imaging examples for completeness. The mnemonic is “CANNOT B”
UIP.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Clinical ImagingAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Cross-sectional imaging of pulmonary fibrosis translating pathology into radiology.Clin Imaging. 2018; 51 (Sep-Oct): 332-336
- Diagnosis of idiopathic pulmonary fibrosis. An official ATS/ERS/JRS/ALAT clinical practice guideline.Am J Respir Crit Care Med. 2018; 198: e44-e68
- Pathologically proved nonspecific interstitial pneumonia: CT pattern analysis as compared with usual interstitial pneumonia CT pattern.Radiology. 2014; 272 (Aug): 549-556
- The temporal heterogeneity of usual interstitial pneumonia on chest CT.Expert Rev Respir Med. 2022; (Oct 13): 1-3
- Update on pulmonary fibrosis: not all fibrosis is created equally.Arch Pathol Lab Med. 2016; 140 (1 March): 221-229
- The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis.Antioxid Redox Signal. 2008; 10 (Feb): 287-301
- Acute exacerbation (acute lung injury of unknown cause) in UIP and other forms of fibrotic interstitial pneumonias.Am J Surg Pathol. 2007; 31 (Feb): 277-284
- The lung parenchyma.in: Chest CT for Non-radiologists. Springer, Cham2018
- Cryptogenic organizing pneumonia.(Sep 18)in: StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL)2020 (2021 Jan–. PMID: 29939651)
- Acute interstitial pneumonia.(Aug 11)in: StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL)2020 (2021 Jan–)
- Acute and subacute idiopathic interstitial pneumonias.Respirology. 2016; 21 (Jul): 810-820
- Glossary of terms for CT of the lungs: recommendations of the Nomenclature Committee of the Fleischner Society.Radiology. 1996; 200: 327-331
- Diagnosis of hypersensitivity pneumonitis in adults. An official ATS/JRS/ALAT clinical practice guideline.Am J Respir Crit Care Med. 2020; 202 (Aug 1): e36-e69
- Obliterative bronchiolitis associated with rheumatoid arthritis: analysis of a single-center case series.BMC Pulm Med. 2018; 18 (Jun 22): 105
- Pulmonary sarcoidosis: typical and atypical manifestations at high-resolution CT with pathologic correlation.Radiographics. 2010; 30 (Oct): 1567-1586
- Respiratory bronchiolitis-interstitial lung disease.Orphanet J Rare Dis. 2014 Jul; 11: 106
- Desquamative interstitial pneumonia: a systematic review of its features and outcomes.Eur Respir Rev. 2020; 29 (Jun 23)190181
- Interstitial lung disease in Sjögren's syndrome: a clinical review.Clin Exp Rheumatol. 2020; 38 Suppl 126 (Jul-Aug): 291-300
- Pulmonary Langerhans' cell histiocytosis in adults.Adv Respir Med. 2017; 85: 277-289
- Hypersensitivity pneumonitis: airway-centered pulmonary fibrosis on chest CT.Respir Investig. 2021; 59 (Nov): 845-848
- Chronic hypersensitivity pneumonitis.J Asthma Allergy. 2016; 9 (Sep 21): 171-181
- Circulatory TGF-beta1 is significantly higher in early stage of pulmonary sarcoidosis.Sarcoidosis Vasc Diffuse Lung Dis. 2018; 35: 213-217
- Is it idiopathic pulmonary fibrosis or not?.J Am Board Fam Med. 2018; 31 (Jan-Feb): 151-162
- The right upper lobe bronchus angle: a tool for differentiating fibrotic and non-fibrotic sarcoidosis.Sarcoidosis Vasc Diffuse Lung Dis. 2020; 37: 99-103
- Probable usual interstitial pneumonia pattern on chest CT: is it sufficient for a diagnosis of idiopathic pulmonary fibrosis?.Eur Respir J. 2020; 55 (Apr 9)1802465
- Evolution of the ‘Indeterminate UIP’ HRCT pattern; a cohort snapshot.Eur Respir J. 2020; 56 (Sep) (2): 786
Article info
Publication history
Accepted:
February 27,
2023
Received in revised form:
January 24,
2023
Received:
November 15,
2022
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2023 Elsevier Inc. All rights reserved.
