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Meningitis as a complication of Sjögren's syndrome

  • Diogo Goulart Corrêa
    Correspondence
    Corresponding author at: Department of Radiology, Clínica de Diagnóstico por Imagem (CDPI)/DASA, Avenida das Américas, 4666, 302A, 303, 307, 325, 326, Barra da Tijuca, Rio de Janeiro, RJ Zip Code: 22640-102, Brazil.
    Affiliations
    Department of Radiology, Clínica de Diagnóstico por Imagem (CDPI)/DASA, Avenida das Américas, 4666, 302A, 303, 307, 325, 326, Barra da Tijuca, Rio de Janeiro, RJ Zip Code: 2640-102, Brazil

    Department of Radiology, Federal Fluminense University, Rua Marquês de Paraná, 303, Centro, Niterói, RJ Zip code: 24070-035, Brazil
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  • Luiz Celso Hygino da Cruz Jr.
    Affiliations
    Department of Radiology, Clínica de Diagnóstico por Imagem (CDPI)/DASA, Avenida das Américas, 4666, 302A, 303, 307, 325, 326, Barra da Tijuca, Rio de Janeiro, RJ Zip Code: 2640-102, Brazil
    Search for articles by this author

      Highlights

      • Meningitis can be a complication of Sjögren's syndrome.
      • Meningitis can be presented as leptomeningitis or pachymeningitis in Sjögren's syndrome.
      • Sjögren's syndrome should be considered in the differential diagnosis of meningeal enhancement.
      • FLAIR sequence can be more sensitive than T1-weighted imaging to detect meningeal gadolinium-enhancement.

      Abstract

      Sjögren's syndrome can be complicated by several neurological manifestations, including aseptic meningitis, which can be manifested with headache, flu-like symptoms, confusion, fever, signs of meningeal irritation, with or without focal neurological symptoms and cranial nerve palsy. Neuroimaging can reveal contrast enhancement in the lepto- or pachymeninges. Therefore, Sjögren's syndrome should be considered in the differential diagnosis of lepto- or pachymeningeal enhancement.

      Keywords

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