Dual-layer spectral CT virtual-non-contrast images aid in parathyroid adenoma analysis and radiation dose reduction: confirmation of findings from dual-energy CT

Published:February 11, 2022DOI:


      • 4D-CT parathyroid scans are increasingly utilized to detect parathyroid adenomas.
      • CT dual-energy VNC images on 4D-CT parathyroid scans reduce radiation dose.
      • CT spectral VNC images on 4D-CT parathyroid scans may also reduce radiation dose.


      4D-parathyroid CT scans have become a mainstay in the evaluation and pre-surgical planning for parathyroid adenomas. Most protocols typically rely on non-contrast images, prior to the arterial and delayed phases. Previous reports with dual-energy CT imaging have highlighted the utility of virtual non-contrast images to help reduce radiation dose while maintaining diagnostic accuracy. Herein, we report two cases of surgically proven parathyroid adenomas diagnosed with 4D-parathyroid CT scans performed on dual-layer spectral scanners, and in retrospect highlight the utility of virtual non-contrast images. To our knowledge, this report provides the first description of virtual non-contrast images from dual-layer spectral CT scanners that could aid in the diagnosis of parathyroid adenomas, confirming similar findings described with dual-energy CT scanners.


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