Streptococcus Intermedius as the cause of sphenoid sinusitis & associated extensive skull base and neck thrombophlebitis & thrombosis

Published:September 23, 2021DOI:


      • Streptococcus Intermedius is a rare cause of acute bacterial sinusitis with greater morbidity due to its pyogenicity.
      • Acute bacterial sinusitis can lead to severe intracranial and head and neck complications when there is venous extension.
      • Central nidus and the causal organism both contribute to the severity of acute bacterial sinusitis and its complications.


      Acute bacterial sinusitis may be complicated by orbital and intracranial involvement and by thrombophlebitis. Its spread across multiple anatomic compartments is facilitated by the interconnected venous anatomy of the head and neck and the virulence of the primary pathogen. We present a rare case of Streptococcus Intermedius (S. Intermedius) acute bacterial sinusitis complicated by extensive skull base involvement including cavernous sinuses and neck vein thrombophlebitis and thrombosis.


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