Highlights
- •This study revealed that the incidence of ascites accompanying thecoma-fibroma was 77.50%.
- •MR images showed tumors could be divide into three types according to the degree of cystic degeneration.
- •This study showed that the incidence of ascites was significantly correlated with tumor size, tumor solidity and serum CA-125 levels.
Abstract
Purpose
To survey the occurrence rate of ascites in patients with thecoma-fibroma and its
potential correlation with tumor MR imaging characteristics.
Methods
A total of 40 patients with surgically proven thecoma-fibroma were enrolled in this
retrospective study. We determined the tumor size, the components (solid or cystic)
and their signal intensity features. Second, we identified ascites according to the
fat-suppressed sagittal T2-weighted imaging sequence and divided all cases into two groups (with or without
ascites). Furthermore, we explored the correlations of ascites with tumor size, tumor
solidity, pathological types, patient's postmenopausal status and serum CA-125 levels
by using the χ2 test.
Results
(1) Among the 40 cases, 15 tumors were fibromas, 15 thecomas, and 10 fibrothecomas.
Nine patients (26.47%) had elevated CA-125 levels (>35.0 U/ml). (2) Thirty-one patients
had ascites (77.50%), 29 of which had a small amount of ascites. Nine cases had no
ascites (22.50%). (3) MRI showed a solid mass in 22 cases (55.0%), cystic mass in
five cases (12.5%) and mixed solid-cystic mass in 13 cases (32.5%). The χ2 test revealed that the incidence of ascites was significantly correlated with tumor
size, tumor solidity and serum CA-125 levels (P < 0.05), but not with menopause and pathological type (P > 0.05).
Conclusion
Our data revealed that the incidence of ascites was 77.50% and was mainly correlated
with tumor size and elevated CA-125 levels. These findings have potential value for
improving the diagnosis and differential diagnosis of thecoma-fibroma.
Keywords
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Article info
Publication history
Published online: August 02, 2021
Accepted:
June 6,
2021
Received in revised form:
June 4,
2021
Received:
November 8,
2020
Identification
Copyright
© 2021 Published by Elsevier Inc.
