Unifocal Langerhans cell histiocytosis of bone: percutaneous navigational bipolar radiofrequency ablation for curative treatment

Published:November 14, 2020DOI:


      • Percutaneous RFA may be considered as a minimally invasive option for safe and effective treatment of LCH of bone.
      • Unique advantages of navigational bipolar radiofrequency ablation system are described.
      • Alternative treatment options for LCH of bone are discussed.


      In this report, the initial clinical experience of authors is described on the novel application of a navigational bipolar radiofrequency ablation electrode system for curative treatment of a painful unifocal Langerhans cell histiocytosis involving the supra-acetabular iliac bone. The technical success and safety of the radiofrequency ablation procedure to achieve cure suggests that this intervention may be utilized in clinical practice as a viable and minimally invasive alternative option, for management of unifocal Langerhans cell histiocytosis.


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