Diffuse pulmonary meningotheliomatosis


      • DPM is a rare disease often incidentally diagnosed on biopsy or autopsy with unclear etiology to date.
      • On imaging, it presents as diffuse randomly distributed micro-nodules and can be confused with metastatic or infectious disease.
      • DPM should be considered in the differential, particularly when radiological features (such as long-term stability) and clinical context make other processes unlikely.


      We report the case of an 80-year-old woman presenting with randomly distributed ground glass nodules in the lungs. Since this imaging appearance can be confusing and can mimic other disease processes, it is important to have an organized approach. In this specific case, the distribution and appearance of nodules, their presence for a prolonged period as well as the clinical context were clues to the diagnosis of diffuse pulmonary meningotheliomatosis (DPM). The final diagnosis was established by surgical biopsy. This article reviews the current literature on DPM, imaging appearance, and an algorithmic approach to the presented case.


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