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Migrating pseudolipoma of Glisson's capsule

      Highlights

      • Pseudolipomas of Glisson’s capsule are benign lesions composed of fat, likely derived from a dislodged epiploic appendage.
      • Pseudolipomas of Glisson’s capsule can migrate in the subcapsular location, unlike metastasis, which can be subcapsular but in a fixed location.

      Abstract

      Pseudolipomas of Glisson's capsule are rare benign subcapsular liver lesions that typically affect older men. They are composed of degenerating fat that is thought to originate from a detached epiploic appendage. On Computed Tomographic (CT) imaging, pseudolipomas of Glisson's capsule are well-circumscribed and hypoattenuating compared to the hepatic parenchyma. This case report examines three consecutive CT studies in the same patient that show the pseudolipoma migrating to a hepatic subcapsular location over a period of 4.5 months. To our knowledge, this is the first documented case of a pseudolipoma migrating over time and it supports the hypothesis of a migrating epiploic appendage forming a pseudolipoma of Glisson's capsule. A comprehensive review of relevant literature and a discussion of the presented case are provided.

      Keywords

      Abbreviations:

      CBC (Complete Blood Count), CMP (Comprehensive Metabolic Panel), UA (Urinalysis), CT (Computed Tomography), CECT (Contrast Enhanced CT), PET (Positron Emission Tomography), PGC (Pseudolipoma of Glisson's Capsule), HU (Hounsfield Units)
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