Migrating pseudolipoma of Glisson's capsule


      • Pseudolipomas of Glisson’s capsule are benign lesions composed of fat, likely derived from a dislodged epiploic appendage.
      • Pseudolipomas of Glisson’s capsule can migrate in the subcapsular location, unlike metastasis, which can be subcapsular but in a fixed location.


      Pseudolipomas of Glisson's capsule are rare benign subcapsular liver lesions that typically affect older men. They are composed of degenerating fat that is thought to originate from a detached epiploic appendage. On Computed Tomographic (CT) imaging, pseudolipomas of Glisson's capsule are well-circumscribed and hypoattenuating compared to the hepatic parenchyma. This case report examines three consecutive CT studies in the same patient that show the pseudolipoma migrating to a hepatic subcapsular location over a period of 4.5 months. To our knowledge, this is the first documented case of a pseudolipoma migrating over time and it supports the hypothesis of a migrating epiploic appendage forming a pseudolipoma of Glisson's capsule. A comprehensive review of relevant literature and a discussion of the presented case are provided.



      CBC (Complete Blood Count), CMP (Comprehensive Metabolic Panel), UA (Urinalysis), CT (Computed Tomography), CECT (Contrast Enhanced CT), PET (Positron Emission Tomography), PGC (Pseudolipoma of Glisson's Capsule), HU (Hounsfield Units)
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