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Myocardial hypoattenuation in cardiac sarcoidosis: CT correlation with CMR, PET and SPECT

  • Peter M. Raimondi
    Affiliations
    Department of Cardiology, North Shore University Hospital, Northwell Health, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY 11030, United States of America
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  • Jay Lisker
    Affiliations
    Department of Cardiology, North Shore University Hospital, Northwell Health, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY 11030, United States of America
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  • Josephine N. Rini
    Affiliations
    Department of Radiology, North Shore University Hospital, Northwell Health, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY 11030, United States of America

    Multimodality Cardiovascular Imaging Laboratory, North Shore University Hospital, Manhasset, NY 11030, United States of America
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  • Taisia Vitkovski
    Affiliations
    Department of Anatomic/Clinical Pathology, North Shore University Hospital, Northwell Health, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY 11030, United States of America
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  • Navid Rahmani
    Affiliations
    Department of Radiology, North Shore University Hospital, Northwell Health, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY 11030, United States of America

    Multimodality Cardiovascular Imaging Laboratory, North Shore University Hospital, Manhasset, NY 11030, United States of America
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  • Jeffrey T. Kuvin
    Affiliations
    Department of Cardiology, North Shore University Hospital, Northwell Health, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY 11030, United States of America
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  • Shahryar G. Saba
    Correspondence
    Corresponding author at: Department of Cardiology, North Shore University Hospital, Northwell Health, Zucker School of Medicine at Hofstra/Northwell, 300 Community Drive, Manhasset, NY 11030, United States of America.
    Affiliations
    Department of Cardiology, North Shore University Hospital, Northwell Health, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY 11030, United States of America

    Department of Radiology, North Shore University Hospital, Northwell Health, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY 11030, United States of America

    Multimodality Cardiovascular Imaging Laboratory, North Shore University Hospital, Manhasset, NY 11030, United States of America
    Search for articles by this author

      Highlights

      • Marked myocardial hypoattenuation noted on contrast-enhanced CT in a patient with cardiac sarcoidosis.
      • Myocardial hypoattenuation correlates with a perfusion defect and LGE on CMR, increased FDG activity on PET and a perfusion defect on SPECT.
      • Contrast-enhanced CT may provide information regarding myocardial tissue characterization.
      • CMR and FDG-PET demonstrate clinical utility for evaluation of cardiac sarcoidosis and monitoring response to therapy.

      Abstract

      We report a marked abnormality in myocardial attenuation on non-gated contrast-enhanced CT in a patient with multiorgan sarcoidosis and correlate our findings with CMR, PET and SPECT. The noteworthy observation of myocardial hypoattenuation, in correspondence with the multimodality cardiovascular imaging findings, suggests that standard contrast-enhanced CT may provide information regarding tissue characterization. This report also demonstrates the independent clinical utility of CMR and PET in the evaluation and management of cardiac sarcoidosis.

      Keywords

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      References

        • Aikawa T.
        • Oyama-Manabe N.
        • Naya M.
        • Ohira H.
        • Sugimoto A.
        • Tsujino I.
        • et al.
        Delayed contrast-enhanced computed tomography in patients with known or suspected cardiac sarcoidosis: a feasibility study.
        Eur Radiol. 2017; 27: 4054-4063
        • Murphy D.J.
        • Subesinghe M.
        • Rashid I.
        • Reyes-Torres E.
        Active cardiac sarcoidosis on standard chest computed tomography.
        Eur Heart J Cardiovasc Imaging. 2018; 19: 1025
        • Nikolaou K.
        • Knez A.
        • Sagmeister S.
        • Wintersperger B.J.
        • Boekstegers P.
        • Steinbeck G.
        • et al.
        Assessment of myocardial infarctions using multidetector-row computed tomography.
        J Comput Assist Tomogr. 2004; 28: 286-292