Abstract
Background
T1-weighted post-contrast MRI is essential in brain protocols. We demonstrate the
feasibility and utility of a 3D non-Cartesian radial acquisition in children.
Purpose
To compare bulk motion artifacts, image quality, and lesion conspicuity in 3D T1-weighted
post-contrast brain MRI between a new fat-suppressed radial gradient-echo and a traditional
non-fat-suppressed inversion-recovery Cartesian gradient-echo sequence.
Material and methods
Images from 53 patients acquired at 3 Tesla were compared. Three radiologists rated
the images in three categories, including the presence of bulk motion and whether
it impacted diagnosis, whether one sequence was preferred over the other in overall
image quality and conspicuity of vascular structures and lesions, and whether diagnosis
was possible if only the new fat-suppressed radial acquisition was obtained.
Results
The Fleiss' kappa for inter-rater agreement was 0.67 for bulk motion and 0.54 for
sequence preference. Of the 53 cases, 56% were identified to have significant motion
on conventional imaging, while only 13% had motion artifacts on the radial acquisition
(p < 0.05). There were no cases where motion was seen on the radial acquisition but
not on conventional imaging. Both sequences were equally preferred in 87% of the cases.
All radiologists agreed that the radial approach had lower gray-white matter contrast
than the conventional inversion-recovery method, but preferred the former for making
diagnosis in uncooperative patients.
Conclusion
We demonstrate the potential utility of a fat-suppressed 3D T1-weighted post-contrast
brain gradient-echo sequence in children. The technique is useful in non-sedate pediatric
imaging due to its reduced sensitivity to bulk motion.
Keywords
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References
- Reducing sedation for pediatric body MRI using accelerated and abbreviated imaging protocols.Pediatr Radiol. 2018; 48: 37-49
- Prospective motion correction improves diagnostic utility of pediatric MRI scans.Pediatr Radiol. 2011; 41: 1578-1582
- Strategies to minimize sedation in pediatric body magnetic resonance imaging.Pediatr Radiol. 2016; 46: 916-927
- Anaesthesia or sedation for MRI in children.Curr Opin Anaesthesiol. 2010; 23: 513-517
- Motion artefacts in MRI: a complex problem with many partial solutions.J Magn Reson Imaging. 2015; 42: 887-901
- Three-dimensional MP-RAGE—an alternative to conventional three-dimensional FLASH sequences for the diagnosis of viscerocranial tumors?.Br J Radiol. 1995; 68: 1316-1324
- Clinical comparison of three-dimensional MP-RAGE and FLASH technqiues for MR imaging of the head.J Magn Reson Imaging. 1991; 1: 493-500
- Comparison of post-contrast 3D T1 MPRAGE, 3D T1 SPACE, and 3D T2 FLAIR MR images in evaluation of meningeal abnormalities at 3T MRI.Br J Radiol. 2017; https://doi.org/10.1259/bjr.20160834
- Contrast-enhanced 3-dimensional SPACE vs. MP-RAGE for the detection of brain metastases: considerations with a 32-channel head coil.Investig Radiol. 2013; 48: 55-60
- Comparison of added value of contrast-enhanced 3D fluid-attenuated inversion recovery and magnetization-prepared rapid acquisition of gradient echo sequences in relation to conventional post-contrast T1-weighted images for the evaluation of leptomeningeal diseases at 3 Tesla.AJNR Am J Neuroradiol. 2010; 31: 868-873
- Gadolinum-enhanced three-dimensional magnetization-prepared rapid gradient-echo (3D MP-RAGE) imaging is superior to spin-echo imaging in delineating brain metastases.Acta Radiol. 2008; 49: 1167-1173
- Three-dimensional, T1-weighted gradient-echo imaging of the brain with a volumetric interpolated examination.AJNR Am J Neuroradiol. 2002; 23: 995-1002
- Three-dimensional radial VIBE sequence for contrast-enhanced imaging: an alternative for reducing motion artifacts in restless children.AJR Am J Roentgenol. 2018; 210: 876-882
- Comparison of brain MR images at 1.5 T using BLADE and rectilinear techniques for patients who move during data acquisition.Am J Neuroradiol. 2012; 33: 77-82
- Free-breathing contrast-enhanced T1-weighted gradient-echo imaging with radial k-space sampling for paediatric abdominopelvic MRI.Eur Radiol. 2014; 24: 320-326
- Respiratory motion-resolved compressed sensing reconstruction of free-breathing radial acquisition for dynamic liver magnetic resonance imaging.Invest Radiol. 2015; 50: 749-756
- High spatiotemporal resolution dynamic contrast-enhanced MR enterography in Crohn disease terminal ileitis using continuous golden-angle radial sampling, compressed sensing, and parallel imaging.AJR Am J Roentgenol. 2015; 204: W663-W669
- Radial T1-weighted magnetic resonance imaging: background, clinical applications, and future directions.Appl Radiol. 2016; 5: 24-33
- Free-breathing quantification of hepatic fat in healthy children and children with nonalcoholic fatty liver disease using a multi-echo 3-D stack-of-radial MRI technique.Pediatr Radiol. 2018; 48: 941-953
- Comparison of Cartesian and radial acquisition on short-tau inversion recovery (STIR) sequences in breast MRI.Radiol Bras. 2017; 50: 216-223
- Evaluation of the orbit using con-trast-enhanced radial 3D fat-suppressed T1-weighted gradient echo (radial-VIBE) sequence.Br J Radiol. 2015; https://doi.org/10.1259/bjr.20140863
- Contrast-enhanced radial 3D fat-suppressed T1-weighted gradient-recalled echo sequence versus conventional fat-suppressed contrast-enhanced T1-weighted studies of the head and neck.AJR Am J Roentgenol. 2014; 203: 883-889
- Free-breathing radial 3D fat-suppressed T1-weighted gradient-echo sequence for contrast-enhanced pediatric spinal imaging: comparison with T1-weighted turbo spin-echo sequence.AJR Am J Roentgenol. 2016; 207: 177-182
- Water excitation MPRAGE: an alternative sequence for postcontrast imaging of the abdomen in noncooperative patients at 1.5 Tesla and 3.0 Tesla MRI.J Magn Reson Imaging. 2008; 27: 1146-1154
- Free-breathing volumetric fat/water separation by combining radial sampling, compressed sensing, and parallel imaging.Magn Reson Med. 2017; 78: 565-576
- Inversion recovery radial MRI with interleaved projection sets.Magn Reson Med. 2006; 55: 1150-1156
- Adaptive bulk motion exclusion for improved robustness of abdominal magnetic resonance imaging.NMR Biomed. 2017; https://doi.org/10.1002/nbm.3830
Article info
Publication history
Published online: February 09, 2019
Accepted:
February 8,
2019
Received in revised form:
September 18,
2018
Received:
August 11,
2018
Identification
Copyright
© 2019 Elsevier Inc. All rights reserved.
