Highlights
- •Intra-tumoral hemorrhagic necrosis is suggestive for uterine sarcoma.
- •High intensity on T1WI is characteristic but the prevalence varies.
- •Susceptibility-weighted MR sequences such as SWAN are sensitive for the blood products.
- •MRI of 10 uterine sarcomas and 24 leiomyomas were evaluated.
- •The accuracy, sensitivity, and specificity for SWAN were 97%, 100%, and 96%, respectively.
Abstract
Purpose
High intensity intra-tumoral hemorrhagic necrosis on T1-weighted images is a suggestive
finding for uterine sarcomas, however, the reported prevalence varies. The purpose
of this study is to evaluate the capability of susceptibility-weighted MR sequences
(SWS) for the diagnosis of uterine sarcomas.
Materials and methods
MR imaging of surgically proven 10 uterine sarcomas and 24 benign leiomyomas were
retrospectively evaluated for the presence of high intensity areas on T1-weighted
images and signal voids on SWS (T2 star-weighted angiography: SWAN).
Results
High intensity areas on T1-weighted images and signal voids on SWS were observed in
40% and 100% of sarcomas, whereas 0% and 4% of leiomyomas, respectively. The accuracy,
sensitivity, and specificity for T1-weighted images were 82%, 40%, and 100%, and for
SWS were 97%, 100%, and 96%, respectively.
Conclusion
The demonstration of intra-tumoral hemorrhage in patients suspected with uterine sarcomas
by SWS may provide valuable diagnostic findings.
Keywords
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Article info
Publication history
Published online: October 13, 2018
Accepted:
October 12,
2018
Received in revised form:
September 13,
2018
Received:
June 18,
2018
Footnotes
☆Declarations of interest: none.
Identification
Copyright
© 2018 Elsevier Inc. All rights reserved.
