Highlights
- •Sonoelastography increases accuracy of Sjögren's syndrome salivary gland involvement.
- •It increases effectiveness when added to B-mode US.
- •It gives measurement of strain ratio, which is a semi-quantitative value.
Abstract
Objective
Our study aimed to assess the pathological sonoelastographic changes in the major
salivary glands and to demonstrate the diagnostic effectiveness of Sonoelastography
as an additional method to US in Sjögren's syndrome.
Methods
Fifty eight patients with primary Sjögren's syndrome (pSS) were selected according
to the American-European Consensus Group Classification criteria. Twenty five healthy
volunteers involved in this study. All patients were evaluated with B-mode and elastography
by using Hitachi EUB 7500 digital ultrasound equipment. All subjects were female.
The sonoelastography examination, which allowed us to assess the elasticity of the
parenchyma, was performed and strain ratios were measured by comparing with the adjacent
tissues.
Results
Statistically significant differences were found between the pSS and control groups
for the elastographic scores and strain ratios (p < 0.001). The highest sensitivity and specificity levels were obtained when the strain
ratio cut-off value was taken as 1.55 for the submandibular gland and 2.45 for the
parotid gland (sensitivity and specificity were 83% and 88% respectively for the submandibular
gland and 83% and 92% respectively for the parotid gland). However, no statistically
significant differences were found between the disease duration and the elasticity
scores or strain ratios in pSS group (p > 0.05).
Conclusion
US examination is an efficient method to assess major salivary gland involvement in
the diagnosis of pSS. Sonoelastography is a modality which can contribute to the diagnosis
by improving specificity in the differential diagnosis of pSS. Strain ratio measurement,
which is a semi-quantitative method, increases the diagnostic effectiveness by providing
high sensitivity, specificity, and negative predictive values.
Keywords
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Article info
Publication history
Published online: April 14, 2018
Accepted:
April 12,
2018
Received in revised form:
April 11,
2018
Received:
December 8,
2017
Identification
Copyright
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