Highlights
- •Vaginal spindle cell epitheliomas are rare, benign tumors.
- •MRI characteristics include T1 isointensity, T2 hyperintensity, homogeneous enhancement, and diffusion restriction.
- •Histology includes epithelial and mesodermal markers with possible Mullerian, urogenital sinus, or pluripotential origins.
- •These lesions are no longer considered mixed tumors of myoepithelial origin.
- •Management is complete surgical resection.
Abstract
Spindle cell epithelioma of the vagina is a benign entity with fewer than sixty cases
described in the literature, and only two with limited imaging findings, since the
early 1950s. Early pathology literature suggested the lesions were mixed tumors of
myoepithelial origin, but subsequent studies have found relatively few immunohistochemical
characteristics in common with other mixed cell tumors. More recently, Mullerian,
urogenital sinus epithelial, and pluripotential cell origins have been proposed. Given
lesion rarity and a typical lack of imaging before excision, the imaging appearance
of vaginal spindle cell epitheliomas has not been fully described in the radiology
literature, and without comprehensive pathology correlation. The authors describe
a case of spindle cell epithelioma in a 54-year-old woman which was incidentally discovered
on MRI performed for uterine fibroid embolization planning. Pathology and immunohistochemistry
confirmed the diagnosis.
Keywords
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Article info
Publication history
Published online: March 27, 2018
Accepted:
March 26,
2018
Received in revised form:
March 20,
2018
Received:
November 30,
2017
Identification
Copyright
© 2018 Elsevier Inc. All rights reserved.
