Simplified Bernoulli formula to predict flow limiting stenosis at coronary computed tomography angiography

Published:February 06, 2018DOI:


      • Estimated energy loss (EEL) increases with FFR reduction.
      • EEL could be calculated very easily without complex computation.
      • EEL could predict FFR ≤ 0.80 with an accuracy of 83%.
      • The best cutoff of EEL to predict FFR ≤ 0.80 was 1.17.
      • Ischemia analysis using coronary CT would become easier.



      To compare the diagnostic performance of estimated energy loss (EEL) with diameter stenosis (DS) to estimate significant stenosis by fractional flow reserve (FFR).

      Materials and methods

      One hundred twenty-five patients were included. EEL was calculated using DS, lesion length, minimal lumen area and left ventricular volume. FFR ≤ 0.80 was determined significant.


      EEL improved the accuracy from 63% (95% confidence interval (CI): 55–72%) to 83% (95% CI: 75–89%, p < 0.0001). EEL increased the area under the receiver operating characteristics curve from 0.63 to 0.85 (p < 0.0001).


      EEL improved the diagnostic performance to detect functionally significant stenosis than DS.


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