Highlights
- •Automated hepatic fat fraction of 6-p Dixon was accurate correlation with chemical shift imaging.
- •Automated hepatic fat fraction of 6-p Dixon was accurate correlation with CT attenuation value.
- •Imaged fat fraction of 6-p Dixon has the potential for automated hepatic fat quantification.
Abstract
Purpose
To compare automated six-point Dixon (6-p-Dixon) MRI comparing with dual-echo chemical-shift-imaging
(CSI) and CT for hepatic fat fraction in phantoms and clinical study.
Materials and methods
Phantoms and fifty-nine patients were examined both MRI and CT for quantitative fat
measurements.
Results
In phantom study, linear regression between fat concentration and 6-p-Dixon showed
good agreement. In clinical study, linear regression between 6-p-Dixon and dual-echo
CSI showed good agreement. CT attenuation value was strongly correlated with 6-p-Dixon
(R2 = 0.852; P < 0.001) and dual-echo CSI (R2 = 0.812; P < 0.001).
Conclusion
Automated 6-p-Dixon and dual-echo CSI were accurate correlation with CT attenuation
value of liver parenchyma. 6-p-Dixon has the potential for automated hepatic fat quantification.
Keywords
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Article info
Publication history
Published online: June 20, 2017
Accepted:
June 19,
2017
Received in revised form:
May 28,
2017
Received:
February 17,
2017
Footnotes
☆All authors have no conflict of interest.
Identification
Copyright
© 2017 Elsevier Inc. All rights reserved.
