Diagnosis of Grave's disease with pulmonary hypertension on chest CT


      • Loss of normal high attenuation of enlarged thyroid glands on non-enhanced CT can be a diagnostic clue of Grave’s disease.
      • Enlargement of the right atrium or ventricle on CT may suggest presence of pulmonary hypertension.
      • Chest CT has the potential to diagnose Grave’s disease with pulmonary hypertension in the absence of clinical information.



      To evaluate the diagnostic accuracy of chest CT findings to diagnose Grave's disease in pulmonary hypertension.


      We retrospectively evaluated chest CT and the medical records of 13 patients with Grave's disease with (n = 6) or without pulmonary hypertension (n = 7) and in 17 control patients.


      Presence of iso-attenuation of diffusely enlarged thyroid glands compared with adjacent neck muscle on non-enhanced CT as a diagnostic clue of Grave's disease, and assessment of pulmonary hypertension on CT has high diagnostic accuracy.


      Chest CT has the potential to diagnose Grave's disease with pulmonary hypertension in the absence of other information.


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