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Magnetic resonance imaging characteristics of granulomatous mastitis

      Highlights

      • Non-mass enhancement is a routine MRI finding in patients with GM.
      • Clustered ring enhancement is the most common NME pattern.
      • MRI has little discriminatory ability to differentiate GM from a malignant process.
      • MRI for initial work-up or follow-up should be avoided for patients with GM.

      Abstract

      Granulomatous mastitis (GM) is a benign chronic inflammatory condition of the breast. This study was performed to determine the utility of magnetic resonance imaging (MRI) in differentiating GM from malignancy. MRI findings in 12 women with clinical or histopathologically-proven GM were retrospectively reviewed. Non-mass enhancement on MRI was present in all 12 patients with clustered ring enhancement being the most common pattern (n = 7, 58%). Architectural distortion (n = 10, 83%), skin thickening (n = 10, 83%) and focal skin enhancement (n = 10, 83%) were also very common. MRI features of GM are often identical to features considered suspicious for malignancy on MRI.

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      References

        • Hovanessian Larsen L.
        • Peyvandi B.
        • Klipfel N.
        • Grant E.
        • Iyengar G.
        Granulomatous lobular mastitis: imaging, diagnosis, and treatment.
        AJR. 2009; 193: 574-581
        • Dursun M.
        • Yilmaz S.
        • Yahyayev A.
        • et al.
        Multimodality imaging features of idiopathic granulomatous mastitis: outcome of 12 years of experience.
        Radiol Med. 2012; 117: 529-538
        • Kessler E.
        • Wolloch Y.
        Granulomatous mastitis: a lesion clinically simulating carcinoma.
        Am J Clin Pathol. 1972; 58: 642-646
        • Mohammed S.
        • Statz A.
        • Lacross J.S.
        • et al.
        Granulomatous mastitis: a 10 year experience from a large inner city county hospital.
        J Surg Res. 2013; 184: 299-303
        • Scoglietti V.
        • Wooldridge R.
        • Leitch M.
        • et al.
        Development and initiation of a clinical protocol for the treatment of idiopathic granulomatous mastitis.
        J Rare Disord. 2014; 2: 1-6
        • Al-Khawari H.A.
        • Al-Manfouhi H.A.
        • Madda J.P.
        • et al.
        Radiologic features of granulomatous mastitis.
        Breast J. 2011; 17: 645-650
        • Ozturk M.
        • Mavili E.
        • Kahriman G.
        • Akcan A.C.
        • Ozturk F.
        Granulomatous mastitis: radiological findings.
        Acta Radiol. 2007; 48: 150-155
        • Aslan S.
        • Pourbagher A.
        • Colakoglu T.
        Idiopathic granulomatous mastitis: magnetic resonance imaging findings with diffusion MRI.
        Acta Radiol. 2016; 57: 796-801
        • Morris E.A.
        • Comstock C.E.
        • Lee C.H.
        • et al.
        ACR BI-RADS® magnetic resonance imaging.
        in: ACR BI-RADS® atlas, breast imaging reporting and data system. American College of Radiology, Reston, VA2013
        • Tozaki M.
        • Igarashi T.
        • Fukuda K.
        Breast MRI using the VIBE sequence: clustered ring enhancement in the differential diagnosis of lesions showing non-masslike enhancement.
        Am J Roentgenol. 2006; 187: 313-321
        • Uematsu T.
        • Kasami M.
        High-spatial-resolution 3-T breast MRI of nonmasslike enhancement lesions: an analysis of their features as significant predictors of malignancy.
        Am J Roentgenol. 2012; 198: 1223-1230