Highlights
- •Metastatic lesions with a target appearance on HBP in Gd-EOB-DTPA MRI showed a poor response to chemotherapy.
- •Metastatic lesions with a high SI ratio on HBP in Gd-EOB-DTPA MRI showed a poor response to chemotherapy.
- •HBP analysis may be useful to predict the response to chemotherapy and survival.
Abstract
Objectives
To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis
from breast cancer.
Methods
29 metastatic lesions from 12 breast cancer patients who received chemotherapy were
retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified
them as a “target” or “non-target” appearance. The relationship of appearance or SI
ratio with tumor response was analyzed.
Results
A non-target appearance was more frequent in disease control group than in non-control
group [14/18 (77.8%) vs. 4/18 (22.2%)], and it was associated with a better response
[p = 0.048].
Conclusion
HBP analysis may be useful to predict the response to chemotherapy and survival.
Keywords
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Article info
Publication history
Published online: March 08, 2017
Accepted:
March 7,
2017
Received in revised form:
February 11,
2017
Received:
November 30,
2016
Identification
Copyright
© 2017 Elsevier Inc. All rights reserved.
