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Tumefactive demyelination associated with developmental venous anomaly: Report of two cases

Published:February 28, 2017DOI:https://doi.org/10.1016/j.clinimag.2017.02.012

      Highlights

      • We present two cases of tumefactive demyelination (TD) occurring in proximity to a DVA.
      • There has only been one previously reported case of this finding in the literature.
      • Venous derangement has been hypothesized to play a role in demyelination.
      • The DVA or its effects on the adjacent tissue may have potentiated the development of TD.
      • Recognizing imaging features of TD may avoid invasive procedures on this “do not touch” lesion.

      Abstract

      We present two cases of tumefactive demyelination (TD) occurring in close association with a developmental venous anomaly (DVA). Our purpose is to describe the association between demyelinating lesions and venous anomalies, as only one case of TD associated with a DVA has been published in the literature. Appropriate recognition of this “do not touch” lesion may avoid invasive and potentially harmful procedures such as biopsy or resection.

      Abbreviations:

      TD (tumefactive demyelination), DVA (developmental venous anomaly), AML (acute myelogenous leukemia)

      Keywords

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