Highlights
- •Nasal septal perforation prevalence on imaging in an urban population was 2.1%.
- •The high prevalence was associated with intranasal cocaine and heroin use.
- •Radiologists should report septal perforation so patients can be referred for appropriate treatment.
Abstract
Objective
To determine the prevalence of nasal septal perforation (NSP) on CT imaging in an
urban hospital setting.
Methods
Facial bone CT scans from 3708 consecutive patients were reviewed for the presence
of NSP. Size of the perforation was measured in two dimensions. Medical records were
reviewed for possible risk factors.
Results
The prevalence of NSP was 2.05%. The most common risk factor was a history of drug
abuse. Cocaine was the most prevalent drug used.
Conclusion
The prevalence of NSP was more than double of that previously published, likely related
to intranasal drug use in our urban population.
Keywords
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References
- Prevalence of nasal septal perforation: the Skövde population-based study.Rhinology. 2003; 41: 72-75
- Complications of intranasal prescription narcotic abuse.Ann Otol Rhinol Laryngol. 2002; 111
- Midline palatal perforation.J Oral Maxillofac Surg. 1999 Aug; 57: 990-995
- Narcotic septal perforations due to drug addiction.JAMA. 1962 Mar 24; 179: 964-965
- Cocaine-related syndrome and palatal reconstruction: report of a series of cases.Int J Oral Maxillofac Surg. 2007 Aug; 36 (Epub 2007 Jul 20): 721-727
- A new cocaine abuse complex. Involvement of nose, septum, palate, and pharynx.Arch Otolaryngol Head Neck Surg. 1989 Feb; 115: 235-237
- Illicit and licit drugs causing perforation of the nasal septum.J Forensic Sci. 1982 Oct; 27: 958-962
- Nasal septal perforation: prevention and management.Ann Plast Surg. 1980 Dec; 5 (2–9): 45
- Hard palate perforation in cocaine abusers: a systematic review.Clin Oral Investig. 2010 Dec; 14: 621-628
- An unusual nasal foreign body in an unusual nasal cavity.J Emerg Med. 2004 May; 26: 453-455
- Snorting benzodiazepines.Am J Drug Alcohol Abuse. 1991; 17: 457-468
- Nasal septum perforation due to methamphetamine abuse.Iran J Otorhinolaryngol. 2013 Winter; 25: 53-56
- Harm reduction centers (“CAARUD”): privileged places for warning signal detection in addictovigilance.Therapie. 2012 Sep-Oct; 67: 437-445
- Drug use trends in New York City: 2013.Proceedings of the Community Epidemiology Work Group, June2014
- Effect of morphine on resistance to infection.J Infect Dis. 1983 Oct; 148: 656-666
- The relevance of opioids and opioid receptors on immunocompetence and immune homeostasis.Proc Soc Exp Biol Med. 1996 Dec; 213: 248-257
- Benyamin R opioid therapy and immunosuppression: a review.Am J Ther. 2004 Sep-Oct; 11 (Review): 354-365
- Palatal perforation associated with intranasal prescription narcotic abuse.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 May; 99: 594-597
- Intranasal hydrocodone-acetaminophen abuse induced necrosis of the nasal cavity and pharynx.Laryngoscope. 2012 Nov; 122: 2378-2381
- Deleterious effect of smoking and nasal septal deviation on mucociliary clearance and improvement after septoplasty.Am J Rhinol Allergy. 2009 Jan-Feb; 23: 2-7
- Menzel ML nasal sprays and perforation of the nasal septum.JAMA. 1985 Apr 12; 253: 2046
- Nasal septal perforation associated with topical corticosteroid therapy.J Pediatr. 1984; 105: 840-841
- Intranasal steroids and septum perforation–an overlooked complication? A description of the course of events and a discussion of the causes.Rhinology. 1998 Sep; 36: 128-132
- Acquired immune deficiency syndrome (AIDS) presenting as a nasal septal perforation.Rhinology. 1999 Jun; 37: 93-95
Article info
Publication history
Published online: February 18, 2017
Accepted:
February 17,
2017
Received in revised form:
January 31,
2017
Received:
October 2,
2016
Footnotes
☆The study was approved by our local Institutional Review Board.
☆None of the authors have any conflict of interest or disclosure to report.
Identification
Copyright
© 2017 Elsevier Inc. All rights reserved.