Highlights
- •Hybrid Iterative reconstruction with low dose CACS CT enables stable coronary calcium quantification as full dose FBP.
- •Using HIR low dose CACS, no patient changed risk group from positive to zero or vice versa.
- •Automatic exposure control allowed standardization of image quality and radiation dose exposure.
Abstract
Introduction
We sought to validate whether low dose CACS CT with hybrid IR (HIR) could replace
standard dose filtered back projection (FBP).
Method
We enrolled 100 patients to undergo low dose CACS CT with HIR, in addition to routine
full dose FBP.
Results
No significant difference between full and low dose CT in Agatston score 138.2 ± 360.6 vs. 137.3 ± 356.4 (p = 0.272) or calcium mass score 19 ± 48.3 vs. 18.7 ± 49 (p = 0.8), respectively. Bland–Altman analysis showed no systematic bias. Calcium volume
difference was statistically significant 57.2 ± 134 vs. 55.1 ± 130.2 (p = 0.001).
Conclusion
Low dose CT for calcium scoring with HIR enables stable CACS Agatston score and calcium
mass quantification as compared to full dose FBP.
Graphical abstract
Graphical Abstract
Abbreviations:
CACS (coronary artery calcium score), HIR (hybrid iterative reconstruction), FBP (filtered back projection), FD (full dose), LD (low dose), BMI (body mass index), DLP (dose-length product)Keywords
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Article info
Publication history
Published online: February 01, 2017
Accepted:
January 31,
2017
Received in revised form:
January 17,
2017
Received:
November 8,
2016
Identification
Copyright
© 2017 Elsevier Inc. All rights reserved.
