Highlights
- •The rate of malignancy after follow-up MRI of the prostate in PI-RADS 3 lesions was 4% (1/23).
- •In follow-up MRI maximal diameter of PI-RADS 3 lesions was significantly smaller and ADC-average was significantly higher than in baseline MRI.
- •The NPV of mp-MRI for malignancy in PI-RADS 3 lesions was 96%.
- •The rate of malignancy after follow-up MRI of the prostate in PI-RADS 4 lesions with negative initial core biopsy was 69% (9/13).
For PI-RADS 4 lesions with initial negative biopsy an instant repeat biopsy should
be performed.
Abstract
Objective
To determine the rate of malignancy after follow-up MR imaging of the prostate in
PI-RADS 3 lesions without core biopsy and PI-RADS 4 lesions after negative initial
core biopsy.
Materials and methods
We performed follow-up MRI in 46/72 (64%) patients with PI-RADS 3 lesions and 26/72
(36%) patients with PI-RADS 4 lesions in baseline MRI.
Results
The rate of malignancy in PI-RADS 3 lesions was 4% (2/46) and in PI-RADS 4 lesions
69% (18/26).
Conclusions
Follow-up MRI for PI-RADS 3 lesions should be performed. For PI-RADS 4 lesions with
initial negative biopsy we recommend an instant repeat core biopsy.
Keywords
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Article info
Publication history
Published online: January 30, 2017
Accepted:
January 27,
2017
Received in revised form:
January 12,
2017
Received:
October 6,
2016
Identification
Copyright
© 2017 Elsevier Inc. All rights reserved.
