Abstract
Purpose
To determine the sensitivity of magnetic resonance (MR)-enterography for the detection
of neuroendocrine tumors of the small-bowel (NETSB) and analyze the imaging presentation
of NETSB on MR-enterography.
Patients & Methods
The MR-enterography studies (including HASTE, TruFISP, and 3D VIBE MR sequences before
and after intravenous administration of a gadolinium-chelate) of 19 patients with
pathologically confirmed NETSB were blindly reviewed. Images were analyzed with respect
to imaging presentation. Sensitivity of MR-enterography as well as that of each individual
MR-enterography sequence for the diagnosis of NETSB was estimated with 95% confidence
intervals (CIs). Comparisons between individual MR-enterography sequences were performed
using the McNemar test.
Results
Twenty-seven NETSBs were confirmed in 19 patients. Overall sensitivity of MR-enterography
for NETSB detection was 74% (20/27; 95% CI: 54–89%) on a per-lesion basis. On a per-patient
basis, MR-enterography had a sensitivity of 95% (18/19; 95% CI: 74–100%) for the detection
of NETSB. Best degrees of sensitivity were achieved with 3D VIBE MR-enterography sequences
after intravenous administration of a gadolinium-chelate (Se=95%; 18/19) by comparison with HASTE (Se=26%; 5/19) and TruFISP (Se=26%; 5/19) sequences (P=.00022). Visible focal small-bowel mass, mesenteric stranding, and mesenteric mass
were found in 16/19 (84%), 17/19 (89%), and 15/19 (79%) patients, respectively.
Conclusion
MR-enterography shows highly suggestive features for the diagnosis of NETSB and has
high degrees of sensitivity for the diagnosis of NETSB on a per-patient basis.
Keywords
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Article info
Publication history
Published online: January 15, 2016
Accepted:
December 20,
2015
Received:
October 15,
2015
Identification
Copyright
© 2016 Elsevier Inc. All rights reserved.
