Advertisement

Preoperative diffusion-weighted imaging value of rectal cancer: preoperative T staging and correlations with histological T stage

  • Zhi-hua Lu
    Affiliations
    Medical Imaging Center, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China

    Department of Radiology, Affiliated Changshu Hospital of Soochow University, 1 Shuyuan Road, Changshu, Jiangsu 215500, China
    Search for articles by this author
  • Chun-hong Hu
    Correspondence
    Corresponding author. Medical Imaging Center, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China. Tel.: +86-512-65223637.
    Affiliations
    Medical Imaging Center, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China
    Search for articles by this author
  • Wei-xin Qian
    Affiliations
    Department of Radiology, Affiliated Changshu Hospital of Soochow University, 1 Shuyuan Road, Changshu, Jiangsu 215500, China
    Search for articles by this author
  • Wen-hong Cao
    Affiliations
    Department of Radiology, Affiliated Changshu Hospital of Soochow University, 1 Shuyuan Road, Changshu, Jiangsu 215500, China
    Search for articles by this author
Published:December 18, 2015DOI:https://doi.org/10.1016/j.clinimag.2015.12.006

      Abstract

      Purpose

      To assess the ability of diffusion-weighted imaging (DWI) for evaluating T stage and correlation with histological T stage of rectal cancer.

      Method

      The diagnostic accuracy, sensitivity, and specificity of T2WI and DWI combined with T2WI for T stage were evaluated. Mean tumor apparent diffusion coefficient (ADC) was compared with histological T stage.

      Result

      There were no significant differences in the diagnostic accuracy, sensitivity, and specificity no matter what kind of T stage was concerned. The difference between ADC values and histological T stage were significantly different.

      Conclusion

      DWI was useful for evaluating T stage of rectal cancer. The ADC may predict the histological grade.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Clinical Imaging
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Li M
        • Gu J
        Changing patterns of colorectal cancer in China over a period of 20 years.
        World J Gastroenterol. 2005; 11: 4685-4688
        • Påhlman L
        • Hohenberger W
        • Günther K
        • Fietkau R
        • Metzger U
        Is radiochemotherapy necessary in the treatment of rectal cancer?.
        Eur J Cancer. 1998; 34: 438-448
        • Påhlman L
        Neoadjuvant and adjuvant radio- and radio-chemotherapy of rectal carcinomas.
        Int J Colorectal Dis. 2000; 15: 1-8
        • Merkel S
        • Mansmann U
        • Siassi M
        • Papadopoulos T
        • Hohenberger W
        • Hermanek P
        The prognostic inhomogeneity in pT3 rectal carcinomas.
        Int J Colorectal Dis. 2001; 16: 298-304
        • Cho SH
        • Kim SH
        • Bae JH
        • Jang YJ
        • Kim HJ
        • Lee D
        • et al.
        Prognostic stratification by extramural depth of tumor invasion of primary rectal cancer based on the radiological society of North America proposal.
        AJR Am J Roentgenol. 2014; 202: 1238-1244
        • Keane C
        • Young M
        Accuracy of magnetic resonance imaging for preoperative staging of rectal cancer.
        ANZ J Surg. 2014; 84: 758-762
        • Laghi A
        • Ferri M
        • Catalano C
        • Baeli I
        • Iannaccone R
        • Iafrate F
        • et al.
        Local staging of rectal cancer with MRI using a phased array body coil.
        Abdom Imaging. 2002; 27: 425-431
        • Beets-Tan RG
        • Beets GL
        • Vliegen RF
        • Kessels AG
        • Van Boven H
        • De Bruine A
        • et al.
        Accuracy of magnetic resonance imaging in prediction of tumour-free resection margin in rectal cancer surgery.
        Lancet. 2001; 357: 497-504
        • Brown G
        • Richards CJ
        • Newcombe RG
        • Dallimore NS
        • Radcliffe AG
        • Carey DP
        • et al.
        Rectal carcinoma: thin-section MR imaging for staging in 28 patients.
        Radiology. 1999; 211: 215-222
        • Curvo-Semedo L
        • Lambregts DM
        • Maas M
        • Beets GL
        • Caseiro-Alves F
        • Beets-Tan RG
        Diffusion-weighted MRI in rectal cancer: apparent diffusion coefficient as a potential noninvasive marker of tumor aggressiveness.
        J Magn Reson Imaging. 2012; 35: 1365-1371
        • Akashi M
        • Nakahusa Y
        • Yakabe T
        • Egashira Y
        • Koga Y
        • Sumi K
        • et al.
        Assessment of aggressiveness of rectal cancer using 3-T MRI: correlation between the apparent diffusion coefficient as a potential imaging biomarker and histologic prognostic factors.
        Acta Radiol. 2013; 55: 524-531
        • Miller FH
        • Hammond N
        • Siddiqi AJ
        • Shroff S
        • Khatri G
        • Wang Y
        • et al.
        Utility of diffusion-weighted MRI in distinguishing benign and malignant hepatic lesions.
        J Magn Reson Imaging. 2010; 32: 138-147
        • Sakurada A
        • Takahara T
        • Kwee TC
        • Yamashita T
        • Nasu S
        • Horie T
        • et al.
        Diagnostic performance of diffusion-weighted magnetic resonance imaging in bladder cancer: potential utility of apparent diffusion coefficient values as a biomarker to predict clinical aggressiveness.
        Eur Radiol. 2011; 21: 2178-2186
        • Verma S
        • Rajesh A
        • Morales H
        • Lemen L
        • Bills G
        • Delworth M
        • et al.
        Assessment of aggressiveness of prostate cancer: correlation of apparent diffusion coefficient with histologic grade after radical prostatectomy.
        AJR Am J Roentgenol. 2011; 196: 374-381
        • Costtini M
        • Belli P
        • Rinaldi P
        • Bufi E
        • Giardina G
        • Franceschini G
        • et al.
        Diffusion-weighted imaging in breast cancer: relationship between apparent diffusion coefficient and tumour aggressiveness.
        Clin Radiol. 2010; 65: 1005-1012
        • Feng Q
        • Yan YQ
        • Zhu J
        • Xu JR
        T staging of rectal cancer: accuracy of diffusion-weighted imaging compared with T2-weighted imaging on 3.0 tesla MRI.
        J Dig Dis. 2014; 15: 188-194
        • Kaur H
        • Choi H
        • You YN
        • Rauch GM
        • Jensen CT
        • Hou P
        • et al.
        MR imaging for preoperative evaluation of primary rectal cancer: practical considerations.
        Radiographics. 2012; 32: 389-409
        • Attenberger UI
        • Pilz LR
        • Morelli JN
        • Hausmann D
        • Doyon F
        • Hofheinz R
        • et al.
        Multi-parametric MRI of rectal cancer - do quantitative functional MR measurements correlate with radiologic and pathologic tumor stages?.
        Eur J Radiol. 2014; 83: 1036-1043
        • Gooden MJ
        • de Bock GH
        • Leffers N
        • Daemen T
        • Nijman HW
        The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis.
        Br J Cancer. 2011; 105: 93-103