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Frequency of hemorrhagic complications on abdominal CT in patients with warfarin therapy

  • Sunyoung Lee
    Affiliations
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
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  • Dongil Choi
    Correspondence
    Corresponding author. Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81, Irwon-ro, Gangnam-gu, Seoul, 135-710, Republic of Korea. Tel.: +82-2-3410-2518; fax: +82-2-3410-0084.
    Affiliations
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
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  • Woo Kyoung Jeong
    Affiliations
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
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  • Kyoung Doo Song
    Affiliations
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
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  • Ji Hye Min
    Affiliations
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
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  • Ah Yeong Kim
    Affiliations
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
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  • Mimi Kim
    Affiliations
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
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Published:December 17, 2015DOI:https://doi.org/10.1016/j.clinimag.2015.12.005

      Abstract

      Objective

      To evaluate the frequency of hemorrhagic complications on abdominal computed tomography (CT) in patients with warfarin therapy and its correlation with intensity of anticoagulation.

      Materials and methods

      We included 646 patients who received warfarin therapy with international normalized ratio (INR) greater than 3.0 and abdominal CT within 1 month after INR measurement.

      Results

      Seventy-four patients (11.5%) showed hemorrhagic complications on abdominal CT. Frequency of hemorrhagic complications significantly correlated with intensity of anticoagulation (P<.001).

      Conclusion

      Hemorrhagic complications on abdominal CT in patients with warfarin therapy were not rare, and it occurred more frequently in patients with higher INR.

      Abbreviation:

      INR (International Normalized Ratio)

      Keywords

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