Abstract
Purpose
To compare T1-weighted (T1W) fast spin echo (FSE) to T1W 3-dimensional gradient recalled
echo (LAVA) with fat water separation (FLEX) in prostate cancer (PCa).
Methodology
With institutional review board waiver, 39 patients underwent 3-T magnetic resonance
imaging including T1W LAVA FLEX (157 s)/T1W FSE (316 s). Two radiologists assessed (a) image quality/sharpness, (b) presence/severity of
artifacts, and (c) skeletal (N=22)/nodal (N=9) metastases. Results were compared using Wilcoxon signed-rank test/receiver operator
characteristic analysis.
Results
With T1W LAVA FLEX, image quality/sharpness improved (P<.001) with less motion (P=.002–.03) and no difference in phase-encoding artifact (P>.05). One patient had moderate fat/water swap.
Detection of skeletal metastases was unchanged (P>.05) and nodal metastases either improved (P=.002) or were comparable (P=.16) using T1W LAVA FLEX.
Conclusion
T1W LAVA FLEX improves image quality, lessens motion artifact, and is comparable or
improves detection of metastases in PCa with reduction in acquisition time.
Keywords
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Article info
Publication history
Published online: December 03, 2015
Accepted:
November 19,
2015
Received in revised form:
November 10,
2015
Received:
August 9,
2015
Footnotes
☆There was no funding provided for the organization of this manuscript. Author EB is a GE employee, and all other authors have no disclosures.
Identification
Copyright
© 2015 Elsevier Inc. All rights reserved.
