Abstract
Purpose
To calculate bone marrow cellularity from MRI and correlate with bone marrow biopsy.
Methods
Twenty-seven lymphoma patients with staging bone marrow biopsies and lumbar MRI were
reviewed. Cellularity was calculated from T1 signal intensity measurements=100 – {[(marrow
– CSF)/(subcutaneous fat – CSF)] X 100}.
Results
The histologic cellularities demonstrated significant correlation with iliac bone
MRI cellularity (r=0.59, P=.001). Cellularities increased from T11 to S1. Cellularity decreased with age=67.6
– (age X 0.36).
Conclusions
Marrow cellularity from MRI shows statistically significant correlation with biopsy
and significant differences between vertebral levels and changes with age.
Keywords
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Article info
Publication history
Published online: December 02, 2015
Accepted:
November 13,
2015
Received in revised form:
October 15,
2015
Received:
August 27,
2015
Footnotes
☆Presented at RNSA 2014.
☆☆Disclosures: None.
★IRB: This study was approved by the USC institutional review board.
Identification
Copyright
© 2015 Elsevier Inc. All rights reserved.
