Abstract
Objective
To evaluate the correlation between the magnetic resonance imaging findings of functional
pituitary adenomas and histological distribution of hormone-secreting cells in pituitary
gland.
Methods
Forty-nine patients with pathologically confirmed functional micro and macro pituitary
adenomas were retrospectively reviewed for its location and growth direction.
Results
Micro-prolactin, micro-adrenocorticotropic hormone (ACTH), and micro-growth hormone
(GH) producing adenomas showed specific location (P-value <.01). Macro-GH and macro-thyroid-stimulating hormone producing adenomas showed specific
growth direction (P-value <.05), whereas macro-prolactin and macro-ACTH producing adenomas did not.
Conclusion
The functional pituitary microadenomas' location and macroadenomas' growth pattern
correlate well with histological distribution of hormone-secreting cells in pituitary
gland.
Keywords
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Article info
Publication history
Published online: June 03, 2015
Accepted:
May 26,
2015
Received in revised form:
May 16,
2015
Received:
March 23,
2015
Footnotes
☆Disclosures of all authors: nothing to disclose.
Identification
Copyright
© 2015 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
