Abstract
Purpose
Characterize hypertrophic olivary degeneration (HOD) that develops from posterior
fossa masses and their treatments.
Methods
Retrospectively reviewed MR images and clinical data of 10 patients with posterior
fossa masses and HOD.
Results
Eight patients had cerebellar lesions, and two patients had pontine lesions. Lesions
consisted of tumors, demyelination, and nonspecific necrosis. MRI showed T2 hyperintense
signal in the inferior olive a median 86 days after the diagnosis of a posterior fossa
lesion. HOD presented prior to surgery (n=2), after surgery (n=3), after surgery/radiation therapy (n=4), or without treatment (n=1).
Conclusions
HOD may develop from posterior fossa masses and surgical and/or radiation therapy.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Clinical ImagingAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Enlargement of the inferior olivary nucleus in association with lesions of the central tegmental tract or dentate nucleus.Brain. 1961; 84: 341-361
- Hypertrophic olivary degeneration: metaanalysis of the temporal evolution of MR findings.AJNR Am J Neuroradiol. 2000; 21: 1073-1077
- Hypertrophic olivary degeneration after surgical removal of cavernous malformations of the brain stem: report of four cases and review of the literature.Acta Neurochir (Wien). 2008; 150 ([discussion 56]): 149-156
- Hypertrophic olivary degeneration following pontine haemorrhage: hypertensive crisis or cavernous haemangioma bleeding?.J Neurol Neurosurg Psychiatry. 2003; 74: 797-799
- Hypertrophic olivary degeneration: case report in a child.Pediatr Radiol. 1998; 28: 830-831
- Collision in the inferior olive: hypertrophic olivary degeneration complicated by radiation necrosis in brainstem primitive neuroendocrine tumor.Clin Imaging. 2012; 36: 371-374
- Hypertrophic olivary degeneration: MR imaging and pathologic findings.Radiology. 1994; 192: 539-543
- Hypertrophic olivary degeneration in children: four new cases and a review of the literature with an emphasis on the MRI findings.Br J Radiol. 2012; 85: 511-516
- Hypertrophic olivary degeneration after surgical resection of brain tumors.Acta Radiol. 2013; 54: 462-466
- Diffusion tensor imaging in hypertrophic olivary degeneration.AJNR Am J Neuroradiol. 2010; 31: 1729-1731
Article info
Publication history
Published online: June 03, 2015
Accepted:
May 27,
2015
Received in revised form:
May 12,
2015
Received:
March 24,
2015
Footnotes
☆Funding: Miki Hirano was supported by a Medical Student Summer Fellowship from the Brain Tumor Center of Memorial Sloan Kettering Cancer Center.
☆☆Authorship: Design and conceptualization of the study (SK, RJY), analysis and interpretation of the data (MK, VH, SK, RJY), drafting and revising the manuscript (MK, VH, SK, RJY), and final approval of submitted version (MK, VH, SK, RJY).
★Financial disclosures: All authors report no disclosures.
Identification
Copyright
© 2015 Published by Elsevier Inc.
