Abstract
Twenty-two patients with pathologically confirmed glioblastoma who had received concurrent
CCRT with TMZ underwent conventional MRI including T1-weighted imaging(T1WI), T2-weighted
imaging(T2WI), fluid attenuated inversion recovery(FLAIR)and contrast-enhanced T1WI(T1Ce).
Five GLCM texture maps of contrast, energy, entropy, correlation and homogeneity were
generated for each MRI series. Of the aforementioned 5 texture features, the most
significant features were contrast and correlation on T2WI with areas under ROC curve
of 0.883 and 0.892, respectively, and they had the same sensitivity of 75%, specificity
of 100%, accuracy of 86.4%, PPV of 100% and NPV of 76.9% in differentiation true progression
from pseudoprogression.
Keywords
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Article info
Publication history
Published online: April 16, 2015
Accepted:
April 6,
2015
Received in revised form:
March 20,
2015
Received:
January 26,
2015
Footnotes
☆Conflicts of Interest: This work was partly supported by the Science and Technology Planning Project of Guangdong Province (grant no. 2013B021800063) and the Science and Technology Planning Project of Guangzhou (grant no. 2014J4100071).
Identification
Copyright
© 2015 Published by Elsevier Inc.
