Abstract
Objective
In areas with endemic histoplasmosis, incidental pulmonary nodules are common. Rate
of malignancy and applicability of current tracking guidelines in these regions remain
unclear.
Methods
A total of 148 cases of incidental pulmonary nodules tracked with chest computed tomography
were reviewed for radiologic characteristics, diagnosis, number, and size.
Results
Of the nodules, 87.8% were benign and 12.2% malignant; 30% of nodules >20 mm were malignant. Number of nodules (P=.14) and granulomatous disease (P=.71) were not related to malignant diagnosis.
Conclusion
Malignancy was lower than expected in nodules >20 mm. Appropriate tracking guidelines for incidentally discovered nodules in histoplasmosis
endemic regions must be determined.
Abbreviations:
CT (Computed tomography), PET (Positron emission tomography)Keywords
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Article info
Publication history
Published online: November 13, 2014
Accepted:
November 5,
2014
Received in revised form:
October 27,
2014
Received:
July 29,
2014
Footnotes
☆Financial disclosures: The research submitted was not supported by any source of funding.
☆☆Sponsors: The research submitted was not supported by any sponsors.
★Conflict of interest: No conflicts of interest: Whittney Warren, Ronald Markert, Elizabeth Stewart.
★★Funding information: The research submitted was not supported by any source of funding.
☆☆☆Prior presentation: The research submitted has been presented in poster format at the Wright State University Central Research Forum on October 24, 2013, and Dayton Area GME Research Forum on April 24, 2014.
Identification
Copyright
Published by Elsevier Inc.
