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Evaluation of diffusion-weighted MR imaging in the diagnosis of mild acute pancreatitis

      Abstract

      The goal of our study was to determine the diagnostic value of diffusion-weighted magnetic resonance imaging in the identification of acute mild pancreatitis with low Ranson scores. The study group included 22 healthy subjects and 40 patients with mild acute pancreatitis. Patients with Ranson scores of 1–3 were included in the present study. There was a significant reduction in mean pancreatic apparent diffusion coefficient among the acute pancreatitis patients (1.46±2.80×10−3mm2/s) relative to the healthy subjects (1.69±2.26×10−3mm2/s). Diffusion-weighted imaging improves diagnosis of mild acute pancreatitis and enables the differentiation of acute pancreatitis from other diseases involving abdominal pain and other nonspecific findings.

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      References

        • Whitcomb DC
        Clinical practice. Acute pancreatitis.
        N Engl J Med. 2006; 354: 2142-2150
        • Bradley EL
        A clinically based classification system for acute pancreatitis: summary of the International Symposium on Acute Pancreatitis, Atlanta, GA, September 11 through 13, 1992.
        Arch Surg. 1993; 128: 586-590
        • Ranson JH
        • Rifkind KM
        • Roses DF
        • Fink SD
        • Eng K
        • Spencer FC
        Prognostic signs and the role of operative management in acute pancreatitis.
        Surg Gynecol Obstet. 1974; 139: 69-81
        • Roth Y
        • Tichler T
        • Kostenich G
        • Ruiz-Cabello J
        • Maier SE
        • Cohen JS
        • Orenstein A.
        • Mardor Y.
        High-b-value diffusion-weighted MR imaging for pretreatment prediction and early monitoring of tumor response to therapy in mice.
        Radiology. 2004; 232: 685-692
        • Le Bihan D
        • Breton E
        • Lallemand D
        • Grenier P
        • Cabanis E
        • Laval-Jeantet M
        MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders.
        Radiology. 1986; 161: 401-407
        • Muller MF
        • Prasad P
        • Siewert B
        • Nissenbaum MA
        • Raptopoulos V
        • Edelman RR
        Abdominal diffusion mapping with use of a whole-body echo-planar system.
        Radiology. 1994; 190: 475-478
        • Galea N
        • Cantisani V
        • Taouli B
        Liver lesion detection and characterization: role of diffusion-weighted imaging.
        J Magn Reson Imaging. 2013; 37: 1260-1276
        • Rosenkrantz AB
        • Chandarana H
        • Hindman N
        • Deng FM
        • Babb JS
        • Taneja SS
        • Geppert C.
        Computed diffusion-weighted imaging of the prostate at 3T: impact on image quality and tumour detection.
        Eur Radiol. 2013; 23: 3170-3177
        • Scaglione M
        • Casciani E
        • Pinto A
        • Andreoli C
        • De Vargas M
        • Gualdi GF
        Imaging assessment of acute pancreatitis: a review.
        Semin Ultrasound CT MR. 2008; 29: 322-340
        • Lenhart DK
        • Balthazar EJ
        MDCT of acute mild (nonnecrotizing) pancreatitis: abdominal complications and fate of fluid collections.
        AJR Am J Roentgenol. 2008; 190: 643-649
        • Sandrasegaran K
        • Tann M
        • Jennings SG
        • Maglinte DD
        • Peter SD
        • Sherman S
        • Howard T.J.
        Disconnection of the pancreatic duct: an important but overlooked complication of severe acute pancreatitis.
        Radiographics. 2007; 27: 1389-1400
        • Kwak SW
        • Kim S
        • Lee JW
        • Lee NK
        • Kim CW
        • Yi MS
        • Kim G.H.
        • Kang D.H.
        Evaluation of unusual causes of pancreatitis: role of cross-sectional imaging.
        Eur J Radiol. 2009; 71: 296-312
        • Saokar A
        • Rabinowitz CB
        • Sahani DV
        Cross-sectional imaging in acute pancreatitis.
        Radiol Clin North Am. 2007; 45: 447-460
        • Robinson PJ
        • Sheridan MB
        Pancreatitis: computed tomography and magnetic resonance imaging.
        Eur Radiol. 2000; 10: 401-408
        • Kim YK
        • Ko SW
        • Kim CS
        • Hwang SB
        Effectiveness of MR imaging for diagnosing the mild forms of acute pancreatitis: comparison with MDCT.
        J Magn Reson Imaging. 2006; 24: 1342-1349
        • Xiao B
        • Zhang XM
        Magnetic resonance imaging for acute pancreatitis.
        World J Radiol. 2010; 2: 298-308
        • Zhang XM
        • Feng ZS
        • Zhao QH
        • Xiao CM
        • Mitchell DG
        • Shu J
        • Zeng N.L.
        • Xu X.X.
        • Lei J.Y.
        • Tian X.B.
        Acute interstitial edematous pancreatitis: findings on non-enhanced MR imaging.
        World J Gastroenterol. 2006; 12: 5859-5865
        • Thoeny HC
        • De Keyzer F
        Extracranial applications of diffusion-weighted magnetic resonance imaging.
        Eur Radiol. 2007; 17: 1385-1393
        • Yamashita Y
        • Tang Y
        • Takahashi M
        Ultrafast MR imaging of the abdomen: echo planar imaging and diffusion-weighted imaging.
        J Magn Reson Imaging. 1998; 8: 367-374
        • Ichikawa T
        • Erturk SM
        • Motosugi U
        • Sou H
        • Iino H
        • Araki T
        • Fujii H.
        High-b value diffusion-weighted MRI for detecting pancreatic adenocarcinoma: preliminary results.
        AJR Am J Roentgenol. 2007; 188: 409-414
        • Yoshikawa T
        • Kawamitsu H
        • Mitchell DG
        • Ohno Y
        • Ku Y
        • Seo Y
        • Fujii M.
        • Sugimura K.
        ADC measurement of abdominal organs and lesions using parallel imaging technique.
        AJR Am J Roentgenol. 2006; 187: 1521-1530
        • Soyer P
        • Kanematsu M
        • Taouli B
        • Koh DM
        • Manfredi R
        • Vilgrain V
        • Hoeffel C.
        • Guiu B.
        ADC normalization: a promising research track for diffusion-weighted MR imaging of the abdomen.
        Diagn Interv Imaging. 2013; 94: 571-573
        • Barral M
        • Sebbag-Sfez D
        • Hoeffel C
        • Chaput U
        • Dohan A
        • Eveno C
        • Boudiaf M.
        • Soyer P.
        Characterization of focal pancreatic lesions using normalized apparent diffusion coefficient at 1.5-tesla: preliminary experience.
        Diagn Interv Imaging. 2013; 94: 619-627
        • Barral M
        • Soyer P
        • Ben Hassen W
        • Gayat E
        • Aout M
        • Chiaradia M
        • Rahmouni A.
        • Luciani A.
        Diffusion-weighted MR imaging of the normal pacreas: reproducibility and variations of apparent diffusion coefficient measurement at 1.5- and 3.0-tesla.
        Diagn Interv Imaging. 2013; 94: 418-427
        • Akisik MF
        • Sandrasegaran K
        • Jennings SG
        • Aisen AM
        • Lin C
        • Sherman S
        • Rydberg M.P.
        Diagnosis of chronic pancreatitis by using apparent diffusion coefficient measurements at 3.0-T MR following secretin stimulation.
        Radiology. 2009; 252: 418-425
        • Taniguchi T
        • Kobayashi H
        • Nishikawa K
        • Iida E
        • Michigami Y
        • Morimoto E
        • Yamashita R.
        • Miyagi K.
        • Okamoto M.
        Diffusion-weighted magnetic resonance imaging in autoimmune pancreatitis.
        Jpn J Radiol. 2009; 27: 138-142
        • Shinya S
        • Sasaki T
        • Nakagawa Y
        • Guiquing Z
        • Yamamoto F
        • Yamashita Y
        Acute pancreatitis successfully diagnosed by diffusion-weighted imaging: a case report.
        World J Gastroenterol. 2008; 14: 5478-5480