Abstract
For this feasibility study, dynamic contrast-enhanced magnetic resonance imaging (dceMRI)
was performed preoperatively in 9 patients with histologically proven rectal carcinoma.
A total of 41 lymph nodes detected were matched to histopathology. Their contrast
enhancement patterns were evaluated using computer-aided analysis and categorized
in persistent, plateau, and washout curve type. Highest diagnostic accuracy for detecting
malignancy was observed, when less than 31.8% of the voxels within a lymph node demonstrated
a washout curve (sensitivity/specificity of 81.8%/89.7%; area under the curve, AUC=0.87).
In comparison, conventional size measurements revealed lower AUC of 0.81 (sensitivity/specificity
of 75%/72.4%). We conclude that dceMRI might be of diagnostic value for preoperative
lymph node staging.
Keywords
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Article info
Publication history
Published online: June 19, 2014
Accepted:
June 10,
2014
Received in revised form:
May 20,
2014
Received:
January 23,
2014
Identification
Copyright
© 2014 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
