Abstract
Ventilation–perfusion (VQ) single-photon emission computed tomography (SPECT) comprised
the administration of SmartVent (n=386) or Technegas (n=1564) and 200 MBq 99mTc-MAA. 1406 scans were normal, 462 showed PE, 61 showed a singular subsegmental mismatched
defect, 21 scans were non-diagnostic. 26% of scans performed with Technegas showed
PE, compared to 15% with SmartVent. VQ SPECT had a sensitivity of 95.7%, specificity
98.6%, positive predictive value 95.7%, negative predictive value 98.6%. A normal
VQ SPECT scan implied a more than ten-fold lower cause-specific mortality (1 in 1406)
than a scan showing PE (1 in 116). NPV of a negative D-dimer was 94.3%.
Keywords
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Article info
Publication history
Published online: April 24, 2014
Accepted:
April 14,
2014
Received in revised form:
April 7,
2014
Received:
February 21,
2014
Identification
Copyright
© 2014 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
