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Thyroid nodules with suspicious ultrasound findings: the role of ultrasound-guided core needle biopsy

  • Author Footnotes
    1 Tel.: +86 10 55499056.
    Mingbo Zhang
    Footnotes
    1 Tel.: +86 10 55499056.
    Affiliations
    Department of Ultrasound, General Hospital of Chinese PLA, No.28, Fuxing Road, Haidian District, Beijing, China, (100853)
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  • Author Footnotes
    1 Tel.: +86 10 55499056.
    Yan Zhang
    Footnotes
    1 Tel.: +86 10 55499056.
    Affiliations
    Department of Ultrasound, General Hospital of Chinese PLA, No.28, Fuxing Road, Haidian District, Beijing, China, (100853)
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  • Author Footnotes
    1 Tel.: +86 10 55499056.
    Shuai Fu
    Footnotes
    1 Tel.: +86 10 55499056.
    Affiliations
    Department of Ultrasound, General Hospital of Chinese PLA, No.28, Fuxing Road, Haidian District, Beijing, China, (100853)
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  • Author Footnotes
    1 Tel.: +86 10 55499056.
    Faqin Lv
    Footnotes
    1 Tel.: +86 10 55499056.
    Affiliations
    Department of Ultrasound, General Hospital of Chinese PLA, No.28, Fuxing Road, Haidian District, Beijing, China, (100853)
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  • Author Footnotes
    1 Tel.: +86 10 55499056.
    Jie Tang
    Correspondence
    Corresponding author. Department of Ultrasound, General Hospital of Chinese, PLA, No.28 Fuxing Road, Haidian District, Beijing, China, (100853). Tel.: +86 13718980419, +86 10 55499056; fax: +86 1055499255.
    Footnotes
    1 Tel.: +86 10 55499056.
    Affiliations
    Department of Ultrasound, General Hospital of Chinese PLA, No.28, Fuxing Road, Haidian District, Beijing, China, (100853)
    Search for articles by this author
  • Author Footnotes
    1 Tel.: +86 10 55499056.

      Abstract

      The aim of this study was to evaluate the value of core needle biopsy (CNB) in the diagnosis of sonographically suspicious thyroid nodules. We retrospectively reviewed 997 patients with sonographically suspicious thyroid nodules who underwent CNB using pathological results as gold standard. In our result, the accuracy of CNB was 98.0%, and its area under the receiver operating characteristic curve was 0.981. The inconclusive result was in 22 (6.0%) of CNBs. Therefore, CNB demonstrates high rates of conclusive and accurate diagnosis in sonographically suspicious thyroid nodules, which may reduce repeat fine needle aspiration, diagnostic surgery, and unnecessary follow-up.

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