Abstract
Spindle cell oncocytoma of the adenohypophysis is a rare tumor classified by the World
Health Organization as benign with no malignant features. Recent publications have
questioned its identity as a benign tumor, as six postsurgical recurrences of spindle
cell oncocytoma (SCO) have been reported. This case is the first to illustrate the
natural history of the disease due to delayed intervention, as the tumor showed virtually
no growth. This is an important illustrative case to highlight that urgent surgery
may not be required and conservative close serial surveillance MRI may be a valid
management option.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Clinical ImagingAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Tumors of the sellar region. WHO classification of tumours of the central nervous system.4th ed. International Agency for Research on Cancer, Lyon, France2007: 245-246
- Spindle cell oncocytoma of the adenohypophysis: a tumor of folliculostellate cells?.Am J Surg Pathol. 2002; 26: 1048-1055
- Spindle cell oncocytoma with late recurrence and unique neuroimaging characteristics due to recurrent subclinical intratumoral bleeding.J Neurooncol. 2011; 101: 145-154
- Spindle cell oncocytoma of the adenohypophysis: report of a case with a 16-year follow-up.Pathol Res Pract. 2006; 202: 745-750
- Spindle cell oncocytoma of the adenohypophysis—report of two recurrent cases.Am J Surg Pathol. 2005; 29: 247-253
- Recurrent spindle cell oncocytoma of the pituitary, a case report and review of the literature.Pituitary. 2011; 14: 367-370
- Rapidly recurring folliculostellate cell tumor of the adenohypophysis with the morphology of a spindle cell oncocytoma: case report with electron microscopic studies.Clin Neuropathol. 2009; 28: 303-308
- Spindle cell oncocytoma of the adenohypophysis: report of a case with marked cellular atypia and recurrence despite adjuvant treatment.Clin Neuropathol. 2009; 28: 91-95
- Neoplasms of the sellar region.in: Bigner DD MacLendon TE Bruner JM Russel Rubinstein’s pathology of tumors of the central nervous system. 6th ed. Edward Arnold, London1998: 561-677
- Spindle cell oncocytoma of the adenohypophysis: report of two cases.Acta Neuropathol. 2005; 110: 97-99
- Chapter 333. Disorders of the anterior pituitary and hypothalamus.in: Fauci AS Braunwald E Kasper DL Harrison's Principles of Internal Medicine. 17th ed. McGraw Hill Medical, USA2008: 2195-2217
Article info
Publication history
Published online: March 17, 2014
Accepted:
March 10,
2014
Received in revised form:
March 1,
2014
Received:
December 25,
2013
Identification
Copyright
Published by Elsevier Inc.