Abstract
Objective
The objective was to retrospectively study computed tomography (CT) and magnetic resonance
imaging (MRI) findings of adenosquamous carcinoma of the pancreas (PASC).
Materials and Methods
Twelve patients (six women and six men; mean age, 61.3 years; range, 47–78 years)
who presented with PASC as documented by pathologic examination underwent CT (n=10) or both CT and MRI (n=2) examination. Two radiologists evaluated the images and determined the location,
size, margin, internal attenuation or signal intensity, contrast enhancement, and
pattern for each tumor. Additionally, the presence of poorly enhanced areas, upstream
main pancreatic duct (MPD) dilatation, pancreatic atrophy, and peripancreatic tissue
metastasis were evaluated. Images were cross-referenced to surgical and pathologic
findings.
Results
Masses were distributed throughout the pancreas (head, n=6; body, n=1; and tail, n=5). The tumor size ranged from 2.4 to 5.5 cm with an average size of 3.7 cm. Eight
(66.7%) masses were ill defined, and seven (58.3%) were partially exophytic. Twelve
(100%) masses showed heterogeneous and poorly enhanced areas. The lesions showed weak
(n=5), moderate (n=5), or intense (n=2) progressive enhancement. The diameter of MPD in six patients ranged from 3.0 to
5.0 mm with an average of 3.7 mm. Pancreatic atrophy was not found. In 10 patients
(83.3%), masses invaded the peripancreatic tissues. Two patients had metastatic liver
disease at presentation.
Conclusion
PASC typically presented as an ill-defined, hypovascular mass with a poorly enhanced
area, exophytic tendency, and peripancreatic tissue invasion. Lack of pancreatic atrophy
and mild MPD dilatation were also distinct from common duct pancreatic adenocarcinoma.
Keywords
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Article info
Publication history
Published online: September 12, 2013
Accepted:
August 8,
2013
Received in revised form:
April 28,
2013
Received:
July 9,
2012
Identification
Copyright
© 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.