Abstract
The aim of this study was to examine whether positron emission tomography (PET)/computed
tomography (CT) can detect more cases of colorectal cancer (CRC) than serum carcinoembryonic
antigen (CEA), both at initial staging and during surveillance for recurrence. A retrospective
review of 639 CRC patients imaged with PET/CT was performed. PET/CT was superior to
serum CEA in detecting CRC, identifying 2.5 times as many CRC at initial staging compared
to serum CEA and 1.5 times as many CRC recurrences. The current guideline recommendations
of utilizing PET/CT only in the context of a rising serum CEA will miss more than
one third of all CRC recurrences.
Keywords
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Article info
Publication history
Published online: September 03, 2013
Accepted:
April 29,
2013
Received:
January 13,
2013
Footnotes
☆This manuscript or any figure or table in it has not been submitted to any publication previously. None of the authors have any financial or other relationships that might lead to a conflict of interest. The manuscript has been read and approved by all the authors, and the requirements for authorship have been met. Each author believes that the manuscript represents honest work.
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Copyright
© 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
