Abstract
We described our experience with a heterogeneous collection of 200 arterial spin-labeling
(ASL) perfusion cases. ASL imaging was performed on a 1.5-T magnetic resonance imaging
unit with a receive head coil using a second version of quantitative perfusion imaging.
Sixty-four (32%) patients exhibited normal perfusion, 107 (53.5%) patients exhibited
hypoperfusion, and 29 (14.5%) exhibited hyperperfusion. This ASL study illustrates
the usefulness of ASL perfusion studies in a number of pathological conditions and
that perfusion imaging can be implemented successfully in a routine clinical neuroimaging
protocol.
Keywords
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References
- Comparative overview of brain perfusion imaging techniques.J Neuroradiol. 2005; 32: 294-314
- Arterial spin-labeling in routine clinical practice, part 1: technique and artifacts.AJNR Am J Neuroradiol. 2008; 29: 1228-1234
- Arterial spin-labeled MR perfusion imaging: clinical applications.Magn Reson Imaging Clin N Am. 2009; 17: 315-338
- Arterial spin-labeling in routine clinical practice, part 2: hypoperfusion patterns.AJNR Am J Neuroradiol. 2008; 29: 1235-1241
- Arterial spin-labeling in routine clinical practice, part 3: hyperperfusion patterns.AJNR Am J Neuroradiol. 2008; 29: 1428-1435
- Pattern of cerebral hypoperfusion in Alzheimer disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: initial experience.Radiology. 2005; 234: 851-859
- Quantification of blood flow in brain tumors: comparison of arterial spin labeling and dynamic susceptibility-weighted contrast-enhanced MR imaging.Radiology. 2003; 228: 523-532
- Arterial spin-label imaging in patients with normal bolus perfusion-weighted MR imaging findings: pilot identification of the borderzone sign.Radiology. 2009; 252: 797-807
- Pulsed arterial spin labeling applications in brain tumors: practical review.J Neuroradiol. 2008; 35: 79-89
- Susceptibility contrast and arterial spin labeled perfusion MRI in cerebrovascular disease.J Neuroimaging. 2003; 13: 17-27
- Nephrogenic systemic fibrosis: risk factors and incidence estimation.Radiology. 2007; 243: 148-157
- Perfusion-based functional magnetic resonance imaging.Concepts Magn Reson Part A. 2003; 16A: 16-27
- QUIPSS II with thin-slice TI1 periodic saturation: a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling.Magn Reson Med. 1999; 41: 1246-1254
- Siemens USA.(Available at:) (Accessed September 2010)
- Perfusion imaging of brain tumors using arterial spin labeling: correlation with histopathologic vascular density.AJNR Am J Neuroradiol. 2008; 29: 688-693
- Normal cerebral perfusion measurements using arterial spin labeling: reproducibility, stability, and age and gender effects.Magn Reson Med. 2004; 51: 736-743
- ASL perfusion MRI predicts cognitive decline and conversion from MCI to dementia.Alzheimer Dis Assoc Disord. 2010; 24: 19-27
Article info
Publication history
Published online: December 16, 2011
Accepted:
November 3,
2011
Received:
July 13,
2011
Identification
Copyright
© 2012 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
