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The efficacy of apparent diffusion coefficient value calculation in differentiation between malignant and benign thyroid nodules

Published:November 23, 2011DOI:https://doi.org/10.1016/j.clinimag.2011.10.006

      Abstract

      Purpose

      To evaluate the efficacy of apparent diffusion coefficient (ADC) calculation in differentiation between malignant and benign thyroid nodules.

      Methods and materials

      A prospective study was conducted in 52 patients. Diffusion-weighted echoplanar imaging was performed and b factors were taken as 0 and 400 s/mm2.

      Results

      The mean ADC value for malignant thyroid nodules was 0.829±0.179×10−3 mm2/s and that for benign thyroid nodules was 1.984±0.482×10−3 mm2/s. The mean ADC value for malignant nodules was significantly lower than that for benign nodules (P=.0001).

      Conclusion

      ADC value calculation is an effective method in differentiation of malignant thyroid nodules from benign ones.

      Keywords

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