Abstract
Purpose
To evaluate the efficacy of apparent diffusion coefficient (ADC) calculation in differentiation
between malignant and benign thyroid nodules.
Methods and materials
A prospective study was conducted in 52 patients. Diffusion-weighted echoplanar imaging
was performed and b factors were taken as 0 and 400 s/mm2.
Results
The mean ADC value for malignant thyroid nodules was 0.829±0.179×10−3 mm2/s and that for benign thyroid nodules was 1.984±0.482×10−3 mm2/s. The mean ADC value for malignant nodules was significantly lower than that for
benign nodules (P=.0001).
Conclusion
ADC value calculation is an effective method in differentiation of malignant thyroid
nodules from benign ones.
Keywords
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Article info
Publication history
Published online: November 23, 2011
Accepted:
October 7,
2011
Received:
July 11,
2011
Footnotes
☆Conflict of interest: None.
Identification
Copyright
© 2012 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
