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Evaluation of magnetic resonance imaging criteria for Meckel's cave lesion: logistic regression analysis and correlation with surgical findings

  • Zuohua Tang
    Correspondence
    Corresponding authors. Zuohua Tang is to be contacted at Department of Radiology, Eye Ear Nose & Throat Hospital, Fudan University, 83 Fenyang Rd., Shanghai, 200031, China. Tel.: +86 21 64377134x502 or 231, +86 13162366402(Cell); fax: +86 21 64377151. Xiaoyuan Feng, Department of Radiology, Huashan Hospital of Shanghai Medical School, Fudan University, Shanghai, 200040, China. Tel.: +86 21 62489999; fax: +86 21 62489191.
    Affiliations
    Department of Radiology, Huashan Hospital, Eye and ENT Hospital of Shanghai Medical School, Fudan University, Shanghai, 200031, China
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  • Xiaoyuan Feng
    Correspondence
    Corresponding authors. Zuohua Tang is to be contacted at Department of Radiology, Eye Ear Nose & Throat Hospital, Fudan University, 83 Fenyang Rd., Shanghai, 200031, China. Tel.: +86 21 64377134x502 or 231, +86 13162366402(Cell); fax: +86 21 64377151. Xiaoyuan Feng, Department of Radiology, Huashan Hospital of Shanghai Medical School, Fudan University, Shanghai, 200040, China. Tel.: +86 21 62489999; fax: +86 21 62489191.
    Affiliations
    Department of Radiology, Huashan Hospital of Shanghai Medical School, Fudan University, Shanghai, 200040, China
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  • Wen Qian
    Affiliations
    Department of Radiology, Eye and ENT Hospital of Shanghai Medical School, Fudan University, Shanghai, 200031, China
    Search for articles by this author
  • Jichang Song
    Affiliations
    Department of Radiology, Eye and ENT Hospital of Shanghai Medical School, Fudan University, Shanghai, 200031, China
    Search for articles by this author

      Abstract

      Objective

      Our aim was to investigate the statistical preoperative diagnostic criteria of lesions of Meckel's cave (MC) on MRI.

      Materials and methods

      We retrospectively reviewed the MR images with MC lesions in 34 patients. The MR signs were compared with histopathologic and surgical findings in all lesions. Odds ratio values and the confidence intervals of the MRI diagnostic criteria were evaluated by univariate logistic regression.

      Results

      The following three signs of MC on post-contrast T1WI of MRI have been found to represent the most valuable criterion for determination of MC lesion: (1) contrast enhancement, (2) bulging of lateral wall, and (3) the absence of normal MC, with odds ratios of 362.67 (P<.001), 40.38 (P=.001), and 40.38 (P=.001) individually.

      Conclusion

      Contrast enhancement on post-contrast T1WI is the most sensitive MR sign for demonstrating the presence of MC lesion.

      Keywords

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