Advertisement

Does direct MR galactography have the potential to become an alternative diagnostic tool in patients with pathological nipple discharge?

      Abstract

      Purpose

      To compare direct magnetic resonance galactography (dMRG) and conventional galactography (CGal).

      Materials and Methods

      Thirty women underwent CGal and dMRG. Duct localization and the depth of the assumed underlying pathology in CGal and dMRG were analyzed.

      Results

      Comparing CGal and dMRG, there was no significant difference regarding sector localization, but for depth of pathology (P=.023).

      Conclusion

      Duct localization with dMRG was possible with the same reliability as with CGal. Thus, dMRG may have the potential to become an alternative method to CGal.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Clinical Imaging
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Fuchsjäger MH
        • Philipp MO
        • Loewe C
        • Helbich TH
        Diagnostic management of nipple discharge.
        Wien Klin Wochenschr. 2003; 115: 33-39
        • Santen RJ
        • Mansel R
        Benign breast disorders.
        N Engl J Med. 2005; 353: 275-285
        • Lang JE
        • Kuerer HM
        Breast ductal secretions: clinical features, potential uses, and possible applications.
        Cancer Control. 2007; 14: 350-359
        • Tabár L
        • Dean PB
        • Péntek Z
        Galactography: the diagnostic procedure of choice for nipple discharge.
        Radiology. 1983; 149: 31-38
        • Cabioglu N
        • Hunt KK
        • Singletary SE
        • Stephens TW
        • Marcy S
        • Meric F
        • Ross MI
        • Babiera GV
        • Ames FC
        • Kuerer HM
        Surgical decision making and factors determining a diagnosis of breast carcinoma in women presenting with nipple discharge.
        J Am Coll Surg. 2003; 196: 354-364
        • Van Zee KJ
        • Ortega Perez G
        • Minnard E
        • Cohen MA
        Preoperative galactography increases the diagnostic yield of major duct excision for nipple discharge.
        Cancer. 1998; 82: 1874-1880
        • Cardenosa G
        • Doudna C
        • Eklund GW
        Ductography of the breast: technique and findings.
        AJR Am J Roentgenol. 1994; 162: 1081-1087
        • Dinkel HP
        • Trusen A
        • Gassel AM
        • Rominger M
        • Lourens S
        • Muller T
        • Tschammler A
        Predictive value of galactographic patterns for benign and malignant neoplasms of the breast in patients with nipple discharge.
        Br J Radiol. 2000; 73: 706-714
        • Hou MF
        • Huang TJ
        • Liu GC
        The diagnostic value of galactography in patients with nipple discharge.
        Clin Imaging. 2001; 25: 75-81
        • Dawes LG
        • Bowen C
        • Venta LA
        • Morrow M
        Ductography for nipple discharge: no replacement for ductal excision.
        Surgery. 1998; 124: 685-691
        • Daniel BL
        • Gardner RW
        • Birdwell RL
        • Nowels KW
        • Johnson D
        Magnetic resonance imaging of intraductal papilloma of the breast.
        Magn Reson Imaging. 2003; 21: 887-892
        • Krämer SC
        • Rieber A
        • Görich J
        • Aschoff AJ
        • Tomczak R
        • Merkle EM
        • Müller M
        • Brambs HJ
        Diagnosis of papillomas of the breast: value of magnetic resonance mammography in comparison with galactography.
        Eur Radiol. 2000; 10: 1733-1736
        • Morrogh M
        • Morris EA
        • Liberman L
        • Borgen PI
        • King TA
        The predictive value of ductography and magnetic resonance imaging in the management of nipple discharge.
        Ann Surg Oncol. 2007; 14: 3369-3377
        • Orel SG
        • Dougherty CS
        • Reynolds C
        • Czerniecki BJ
        • Siegelman ES
        • Schnall MD
        MR imaging in patients with nipple discharge: initial experience.
        Radiology. 2000; 216: 248-254
        • Rovno HD
        • Siegelman ES
        • Reynolds C
        • Orel SG
        • Schnall MD
        Solitary intraductal papilloma: findings at MR imaging and MR galactography.
        AJR Am J Roentgenol. 1999; 172: 151-155
        • Bhattarai N
        • Kanemaki Y
        • Kurihara Y
        • Nakajima Y
        • Fukuda M
        • Maeda I
        Intraductal papilloma: features on MR ductography using a microscopic coil.
        AJR Am J Roentgenol. 2006; 186: 44-47
        • Schwab SA
        • Uder M
        • Schulz-Wendtland R
        • Bautz WA
        • Janka R
        • Wenkel E
        Direct MR galactography: feasibility study.
        Radiology. 2008; 249: 54-61
        • Yoshimoto M
        • Kasumi F
        • Iwase T
        • Takahashi K
        • Tada T
        • Uchida Y
        Magnetic resonance galactography for a patient with nipple discharge.
        Breast Cancer Res Treat. 1997; 42: 87-90
        • Kurian AW
        • Hartman AR
        • Mills MA
        • Logan LJ
        • Sawyer AM
        • Ford JM
        • Daniel BL
        Magnetic resonance galactography: a feasibility study in women with prior atypical breast duct cytology.
        Breast J. 2008; 14: 211-214
        • Fajardo LL
        • Jackson VP
        • Hunter TB
        Interventional procedures in diseases of the breast: needle biopsy, pneumocystography, and galactography.
        AJR Am J Roentgenol. 1992; 158: 1231-1238
        • Radiology ACo
        American College of Radiology (ACR) Breast Imaging Reporting and Data System Atlas (BI-RADS® Atlas), BI-RADS®—Mammography, Fourth Edition. BI-RADS®—Ultrasound, First Edition. BI-RADS®—MRI, First Edition.
        ACR, Reston (VA)2003
        • Ghanouni P
        • Kurian AW
        • Margolis D
        • Hartman AR
        • Mills MA
        • Plevritis SK
        • Ford JM
        • Daniel BL
        Ductal pattern enhancement on magnetic resonance imaging of the breast due to ductal lavage.
        Breast J. 2007; 13: 281-286