Advertisement

Kikuchi–Fujimoto disease with spontaneous subdural hematoma in a middle-aged Hispanic male

      Abstract

      Kikuchi–Fujimoto disease (KFD) is an uncommon disorder that usually presents in young adults of Asian descent with fever and cervical lymphadenopathy. Clinically, this disease is often misdiagnosed as lymphoma or tuberculosis, and biopsy is needed for confirmation. The authors report an unusual case of KFD in a Hispanic male presenting with a subacute subdural hematoma, whose care was complicated by extranodal features not typically associated with KFD. The clinical, histopathologic, and radiographic manifestations of KFD are discussed.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Clinical Imaging
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Fulcher AS
        Case report: cervical lymphadenopathy due to Kikuchi disease: US and CT appearance.
        J Comput Assist Tomogr. 1993; 17: 131-133
        • Kim TA
        • Lupetin AR
        • Graham C
        CT appearance of Kikuchi–Fujimoto disease.
        Clin Imaging. 1995; 19: 1-3
        • Na DG
        • Chung TS
        • Byun HS
        • Kim HD
        • Ko YH
        • Yoon JH
        Kikuchi disease: CT and MR findings.
        AJNR Am J Neuroradiol. 1997; 18: 1729-1732
        • Bennie MJ
        • Bowles KM
        • Rankin SC
        Necrotizing cervical lymphadenopathy caused by Kikuchi–Fujimoto disease.
        Br J Radiol. 2003; 76: 656-658
        • Kwon SY
        • Kim TK
        • Kim YS
        • Lee KY
        • Lee NJ
        • Seol HY
        CT findings in Kikuchi disease: analysis of 96 cases.
        AJNR Am J Neuroradiol. 2004; 25: 1099-1102
        • Youk JH
        • Kim EK
        • Ko KH
        • Kim MJ
        Sonographic features of axillary lymphadenopathy caused by Kikuchi disease.
        J Ultrasound Med. 2008; 27: 847-853
        • Kikuchi M
        Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phagocytosis.
        Acta Haematol Jpn Nippon Ketsueki Gakkai Zasshi. 1972; 35: 379-380
        • Fujimoto Y
        • Kozima Y
        • Yamaguchi K
        Cervical subacute necrotizing lymphadenitis: a new clinicopathologic entity.
        Naika. 1972; 20: 920-927
        • Kuo TT
        Kikuchi's disease (histiocytic necrotizing lymphadenitis): a clinico-pathologic study of 79 cases with an analysis of histologic subtypes, immunohistology, and DNA ploidy.
        Am J Surg Pathol. 1995; 19: 798-809
        • Lin HC
        • Su CY
        • Huang SC
        Kikuchi's disease in Asian children.
        Pediatrics. 2005; 115: e92-e96
        • Kucukardali Y
        • Solmazgul E
        • Kunter E
        • Oncul O
        • Yildirim S
        • Kaplan M
        KikuchiFujimoto disease: analysis of 244 cases.
        Clin Rheumatol. 2007; 26 ([Epub ahead of print Mar, 15 2006]): 50-54
        • Lee KY
        • Yeon YH
        • Lee BC
        Kikuchi–Fujimoto disease with prolonged fever in children.
        Pediatrics. 2004; 114 ([Epub ahead of print Nov, 15 2004]): e752-e756
        • Wang TJ
        • Yang YH
        • Lin YT
        • Chiang BL
        Kikuchi–Fujimoto disease in children: clinical features and disease course.
        J Microbiol Immunol Infect. 2004; 37: 219-224
        • Fitzsimmons PR
        • Akpan A
        • Michael B
        Kikuchi–Fujimoto disease as a rare cause of fever of unknown origin in a septuagenarian.
        Age Ageing. 2008; 37: 233-234
        • Rudniki C
        • Kessler E
        • Zarfati M
        • Turani H
        • Bar-Ziv Y
        • Zahavi I
        Kikuchi's necrotizing lymphadenitis: a cause of fever of unknown origin and splenomegaly.
        Acta Hematol. 1988; 79: 99-102
        • Dorfman RF
        • Berry GJ
        Kikuchi's histiocytic necrotizing lymphadenitis: an analysis of 108 cases with emphasis on differential diagnosis.
        Semin Diagn Pathol. 1988; 5: 329-345
        • Kubota M
        • Tsukamoto R
        • Kurokawa K
        • et al.
        Elevated serum interferon γ, and interleukin-6 in patients with necrotizing lymphadenitis (Kikuchi's disease).
        Br J Haematol. 1996; 95: 613-615
        • Iguchi H
        • Sunami K
        • Yamane H
        • et al.
        Apoptotic cell death in Kikuchi's disease: a TEM study.
        Acta Otolaryngol. 1998; 538 (Suppl): 250-253
        • Rubio SI
        • Plewinsky TS
        • Sabatini M
        • Poretsky L
        Kikuchi's disease associated with Hashimoto's thyroiditis.
        J Endocrinol Invest. 1996; 19: 136-137
        • Shusang V
        • Marelli L
        • Beynon H
        • Davies N
        • Patch D
        • Dhillon AP
        • Burroughs AK
        Autoimmune hepatitis associated with Kikuchi–Fujimoto's disease.
        Eur J Gastroenterol Hepato. 2008; 20: 79-82
        • Kim CH
        • Hyun OJ
        • Yoo IR
        • Kim SH
        • Sohn HS
        • Chung SK
        Kikuchi disease mimicking malignant lymphoma on FDG PET/CT.
        Clin Nucl Med. 2007; 32: 711-712
        • Kaicker S
        • Gerard PS
        • Kalburgi S
        • Geller MD
        • Hailoo D
        PET-CT scan in a patient with Kikuchi disease.
        Pediatr Radiol. 2008; 38 ([Epub ahead of print Feb 12, 2008]): 596-597
        • Yamazaki Y
        • Tachibana S
        • Kitahara Y
        • Ohwada T
        Promotive factors of chronic subdural hematoma in relation to age.
        No Shinkei Geka. 1996; 24: 47-51
        • Keller TM
        • Chappell ET
        Spontaneous acute subdural hematoma precipitated by cocaine abuse: case report.
        Surg Neurol. 1997; 47 ([discussion 14-5]): 12-14
        • Alimehmeti R
        • Locatelli M
        Epidural B cell non-Hodgkin's lymphoma associated with chronic subdural hematoma.
        Surg Neurol. 2002; 57: 179-182
        • Noursadeghi M
        • Aqel N
        • Pasvol G
        Kikuchi's disease: a rare cause of meningitis?.
        Clin Infect Dis. 2005; 41 ([Epub ahead of print Sept 9, 2005]): e80-e82