Abstract
Purpose
The purpose of this study was to determine the utility of routine transperineal transition
zone (TZ) biopsies.
Materials and Methods
A total of 1028 consecutive patients underwent transrectal ultrasound-guided prostate
biopsies for the first time. Sextant biopsies and additional two-core TZ biopsies
were performed.
Results
Prostate cancer detection rate was increased by sampling two additional cores from
TZ.
Conclusions
Transition zone biopsies might be reserved to improve the detection rate of prostate
cancer in transperineal biopsy protocol.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Clinical ImagingAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Cancer statistics, 2005.CA Cancer J Clin. 2005; 55: 10-30
- The analysis of the relative survival for urological cancer in urban Shanghai.CJCO. 2005; 32: 321-327
- The sextant protocol for ultrasound-guided core biopsies of the prostate underestimates the presence of cancer.Urology. 1997; 50: 562-566
- Prostate cancer diagnosis using a saturation needle biopsy technique after previous negative sextant biopsies.J Urol. 2001; 166: 86-91
- Can power Doppler enhanced transrectal ultrasound guided biopsy improve prostate cancer detection on first and repeat prostate biopsy?.Eur Urol. 2004; 46: 451-456
- Prospective evaluation of lateral biopsies of the peripheral zone for prostate cancer detection.J Urol. 1998; 160: 2111-2114
- Zonal distribution of prostatic adenocarcinoma. Correlation with histologic pattern and direction of spread.Am J Surg Pathol. 1988; 12: 897-906
- An analysis of 148 consecutive transition zone cancers: clinical and histological characteristics.J Urol. 2000; 163: 1751-1755
- Analysis of differences in clinicopathological features between prostate cancers located in the transition and peripheral zones.Int J Urol. 2006; 13: 368-372
- Zonal location of prostate cancer: significance for disease-free survival after radical prostatectomy?.Urology. 2003; 62: 79-85
- Using gray-scale and color and power Doppler sonography to detect prostatic cancer.AJR Am J Roentgenol. 2000; 174: 623-627
- Detection of prostate carcinoma with contrast-enhanced sonography using intermittent harmonic imaging.Cancer. 2005; 104: 2373-2383
- Does transurethral resection of the prostate facilitate detection of clinically significant prostate cancer that is missed with systematic sextant and transition zone biopsies?.Int J Urol. 2002; 9: 95-99
- Are transition zone biopsies still necessary to improve prostate cancer detection? Results from the Tyrol Screening Project.Eur Urol. 2005; 48: 916-921
- Significance of routine transition zone biopsies in Japanese men undergoing transrectal ultrasound-guided prostate biopsies.Int J Urol. 2005; 12: 964-968
- Best approach for prostate cancer detection: a prospective study on transperineal versus transrectal six-core prostate biopsy.Urology. 2003; 61: 961-966
- Indications for transition zone biopsy in the detection of prostatic carcinoma.J Urol. 1997; 157: 556-558
- Indications for ultrasound guided transition zone biopsies in the detection of prostate cancer.J Urol. 1995; 153: 1000-1003
Article info
Publication history
Published online: May 05, 2009
Accepted:
February 19,
2009
Received:
January 15,
2009
Identification
Copyright
© 2010 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
