Abstract
Purpose
To evaluate the safety of using iodized oil in chemoembolization for liver tumors
in patients with previous adverse reactions to iodinated contrast media.
Materials and methods
Records were retrospectively reviewed for all patients with a history of an adverse
reaction to iodinated contrast media who underwent angiography using gadolinium-based
contrast media and/or carbon dioxide at our institution from January 1998 to September
2006. Patients who underwent chemoembolization or hepatic artery infusion for liver
tumors using iodized oil were identified.
Results
There were 84 procedures with use of iodized oil performed in 36 patients. Mild adverse
reactions potentially related to iodized oil were seen in two procedures (2.4%). There
were no moderate or severe adverse reactions (0.0%).
Conclusion
Iodized oil can be safely used in patients with previous adverse reactions to iodinated
contrast media.
Keywords
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References
- Studies on anticancer treatment with an oily anticancer drug injected into the ligated feeding hepatic artery for liver cancer.Cancer. 1983; 52: 2193-2200
- Hepatocellular carcinoma: treatment with intraarterial iodized oil with and without chemotherapeutic agents.Radiology. 1987; 162: 345-351
- A new approach to chemoembolization therapy for hepatoma using ethiodized oil, cisplatin, and gelatin sponge.Cancer. 1987; 60: 1194-1203
- Transcatheter oily chemoembolization of hepatocellular carcinoma.Radiology. 1989; 170: 783-786
- Iodized oil in the treatment of hepatocellular carcinoma.Br J Surg. 1994; 81: 1563-1571
- Chemoembolization of hepatocellular carcinoma.J Vasc Interv Radiol. 2002; 13: S211-S221
- Adverse reactions to ionic and nonionic contrast media. A report from the Japanese Committee on the Safety of Contrast Media.Radiology. 1990; 175: 621-628
- Comparison of the rates of adverse drug reactions. Ionic contrast agents, ionic agents combined with steroids, and nonionic agents.Invest Radiol. 1991; 26: 404-410
- Nonionic low-osmolarity versus ionic high-osmolarity contrast material for intravenous use in patients perceived to be at high risk: randomized trial.Radiology. 1992; 183: 105-110
- Adverse events with radiographic contrast agents: results of the SCVIR Contrast Agent Registry.Radiology. 1997; 203: 611-620
- Gadolinium chelates in angiography and interventional radiology: a useful alternative to iodinated contrast media for angiography.Radiology. 2002; 223: 319-325
- Safety and effectiveness of gadolinium-enhanced multi-detector row spiral CT angiography of the chest: preliminary results in 37 patients with contraindications to iodinated contrast agents.Radiology. 2005; 235: 819-826
- Gadolinium use in spine procedures for patients with allergy to iodinated contrast—experience of 127 procedures.AJNR Am J Neuroradiol. 2006; 27: 1194-1197
- Quality improvement guidelines for transhepatic arterial chemoembolization, embolization, and chemotherapeutic infusion for hepatic malignancy.J Vasc Interv Radiol. 2006; 17: 225-232
- Treatment of hepatocellular carcinoma associated with advanced cirrhosis by transcatheter arterial chemoembolization using autologous blood clot: a preliminary report.Hepatology. 1992; 15: 252-257
- Hepatocellular carcinoma.Lancet. 2003; 362: 1907-1917
- Transarterial chemoembolization for unresectable hepatocellular carcinoma: meta-analysis of randomized controlled trials.Radiology. 2002; 224: 47-54
- Systematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survival.Hepatology. 2003; 37: 429-442
Article info
Publication history
Published online: February 23, 2009
Accepted:
December 1,
2008
Received:
August 20,
2008
Identification
Copyright
© 2009 Elsevier Inc. Published by Elsevier Inc. All rights reserved.